RIKEN structural genomics beamlines at the SPring-8; high throughput protein crystallography with automated beamline operation

  • Go Ueno
  • Hiroyuki Kanda
  • Raita Hirose
  • Koh Ida
  • Takashi Kumasaka
  • Masaki Yamamoto
Article

DOI: 10.1007/s10969-005-9005-5

Cite this article as:
Ueno, G., Kanda, H., Hirose, R. et al. J Struct Funct Genomics (2006) 7: 15. doi:10.1007/s10969-005-9005-5

Abstract

RIKEN Structural Genomics Beamlines, BL26B1 & BL26B2 at the SPring-8, have been constructed for the structural genomics research. The main feature of the beamline is full automation of the successive data collections to maximize the beam-time efficiency. The beamline optics adopted a standard design commonly used for the SPring-8 bending magnet beamlines. Beamline instruments are operated by centralized control system through the computer network to achieve the automatic operation. The core part of the beamline development is a sample management system composed of sample changer robots for laboratory and beamline, and a networked sample database. BL26B1 has started user operation, and the automatic operation with the sample management system has been implemented at BL26B2.

Key words:

automatic operation high throughput crystallography protein crystallography sample changer structural genomics 

Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Go Ueno
    • 1
    • 2
  • Hiroyuki Kanda
    • 1
    • 2
  • Raita Hirose
    • 3
  • Koh Ida
    • 1
    • 4
    • 6
  • Takashi Kumasaka
    • 1
    • 5
  • Masaki Yamamoto
    • 1
  1. 1.SPring-8/RIKENHyogoJapan
  2. 2.Rigaku co.TokyoJapan
  3. 3.PharmAxess, Inc., CASTHyogoJapan
  4. 4.Yokohama City UniversityKanagawaJapan
  5. 5.Tokyo Institute of TechnologyKanagawaJapan
  6. 6.Kitasato UniversityKanagawaJapan

Personalised recommendations