Journal of Radioanalytical and Nuclear Chemistry

, Volume 322, Issue 2, pp 781–790 | Cite as

Optimization of bioleaching high-fluorine and low-sulfur uranium ore by response surface method

  • Zhongkui Zhou
  • Zhihui Yang
  • Zhanxue SunEmail author
  • Gongxin Chen
  • Lingling Xu
  • Qi LiaoEmail author


In order to optimize conditions for bioleaching of the high-fluorine and low-sulfur uranium ore by the test acidophilic consortiums, the central composite design method and response surface method were applied to study the relationships between pyrite addition, pulp density, temperature and uranium recovery rate, respectively. The results showed that the pulp density, pyrite addition and temperature had a significant impact on the uranium recovery rate. The predicted optimum uranium leaching conditions were 2.20% of pyrite addition, 7.69% of pulp density and 31.90 °C of temperature, respectively. The actual uranium leaching rate under the optimal conditions was 94.84%, which was consistent with the predicted values with the model (95.21%). The results were of great significance for a large-scaled bioleaching practice of the high-fluorine and low-sulfur uranium or low-grade uranium ore.


High-fluorine and low-sulfur uranium ore Acidophilic consortium Bioleaching Response surface method Central composite design method 



This work was supported by the National High Technology Research and Development Program of China (No. 2012AA061504) and National Natural Science Foundation of China (No. 41772266, 41662024 and U1501231).


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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2019

Authors and Affiliations

  1. 1.Institute of Environmental Science and Engineering, School of Metallurgy and EnvironmentCentral South UniversityChangshaChina
  2. 2.State Key Laboratory of Nuclear Resources and EnvironmentEast China University of TechnologyNanchangChina
  3. 3.Chinese National Engineering Research Center for Control & Treatment of Heavy Metal PollutionChangshaChina

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