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Journal of Radioanalytical and Nuclear Chemistry

, Volume 322, Issue 2, pp 809–815 | Cite as

Purification of 99Mo and 99mTc from radioactive traces of Nb, Zr, and Y impurities: method applicable in the purification of the spent 100/99Mo–99mTc generator

  • Sankha ChattopadhyayEmail author
  • Sujata Saha Das
  • Madhusmita
  • Md. Nayer Alam
  • Sharmila Banerjee
Article
  • 30 Downloads

Abstract

The aim of this work was to develop a method for purification of the spent 100/99Mo–99mTc generator free from non-isotopic impurities like Nb, Y, Zr and recovery of 99mTc using a Sephadex column and MEK solvent extraction technique, respectively. This study was done by performing simulation experiment with 98Mo(n,γ)99Mo solution doped with the radiotracers of the above said non-isotopic impurities. There was respective adsorption of non-isotopic impurities of Nb, Zr and Y on Sephadex column (99.99%; n = 3) and extraction 99mTc in MEK. The extraction efficiency of pure 99mTc (radionuclidic purity: 99.99%, n = 3) from various Mo solution was 97% (n = 3).

Keywords

Spent 99/100Mo/99mTc generator Purification Sephadex column chromatography MEK solvent extraction 

Notes

Acknowledgements

The authors thank the IAEA (Contract No. 22475) and the Chief Executive, BRIT for his encouragement and support in the work. The authors are grateful to the Director, VECC for his support and cyclotron operators at VECC for target irradiations.

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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2019

Authors and Affiliations

  • Sankha Chattopadhyay
    • 1
    Email author
  • Sujata Saha Das
    • 1
  • Madhusmita
    • 1
  • Md. Nayer Alam
    • 1
  • Sharmila Banerjee
    • 2
  1. 1.Radiopharmaceuticals Laboratory, Regional Centre, Board of Radiation and Isotope Technology (BRIT)Variable Energy Cyclotron Centre (VECC)KolkataIndia
  2. 2.Radiation Medicine CentreBARCParel, MumbaiIndia

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