Separation and purification of 99mTc from 99Mo produced by electron linear accelerator
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Abstract
The medical radionuclide 99Mo was produced by the 100Mo(γ,n) reaction using bremsstrahlung photons generated by an electron linear accelerator. The amount of 99Mo produced was compared to that predicted by calculation using the particles and heavy ion transport code system. From the 99Mo produced, highly pure 99mTc was separated using the so-called technetium master milker, and the chemical yield of 99mTc was 83–99 %. The installation of a new complex using this method and the electron linear accelerator with the preferable specification was suggested, and a possibility to supply the demand of 99mTc was discussed and shown.
Keywords
Molybdenum-99 Technetium-99m Technetium master milker Bremsstrahlung photon Electron linear acceleratorNotes
Acknowledgments
We thank Mr. N. Abe (Kyoto University Research Reactor Institute, KURRI) for the operation of the LINAC at KURRI. The authors express their gratitude to the members of the LINAC group in KURRI for the arrangement of machine time. This study was supported by a grant-in-aid from Kansai Genshiryoku Kondankai (to SS). This study was supported by a grant-in-aid from the Ministry of Education, Science and Culture in Japan (KAKENHI 25790081, 16K15580 for SS, 16K15579 for TO).
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