Development of a flow-sheet for the radiochemical processing of irradiated sulphate targets for the production of carrier-free 32P
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Abstract
Carrier-free 32P was produced in KAlpakkam MINI reactor (KAMINI) via 32S (n, p) 32P using its small fast flux component. This method has established the flow-sheet for the production of 32P from sulphate targets such as magnesium sulphate and strontium sulphate which can withstand high temperatures of fast reactors unlike the conventionally used sulphur powder. The chemical processing involved (i) struvite precipitation method for magnesium sulphate and (ii) co-precipitation with ferric hydroxide method for strontium sulphate.
Keywords
Radiopharmaceuticals Fast breeder test reactor KAMINI reactor Fast flux Struvite 32PNotes
Acknowledgments
We gratefully acknowledge the operational personnel of KAMINI reactor who helped for the target irradiations in the above experiments.
References
- 1.Atkins HL (1998) Appl Radiat Isot 49:277–283CrossRefGoogle Scholar
- 2.Murty Goddu S, Anupam B, Lionel GB, Wesley EB, Dandamudi VR, Roger WH (2000) J Nucl Med 41:941–951Google Scholar
- 3.Silberstein EB, Elgazzar AH, Kapilivsky A (1992) Semin Nucl Med 22:17–27CrossRefGoogle Scholar
- 4.Ackery D, Yardley J (1993) Semin Oncol 20:27–31Google Scholar
- 5.Silberstein EB (2005) Semin Nucl Med 3:152–158CrossRefGoogle Scholar
- 6.Lewington VJ (2005) J Nucl Med 46:38S–47SGoogle Scholar
- 7.Pandit Taskar N, Batraki M, Chaitanya RD (2004) J Nucl Med 45(8):1358–1365Google Scholar
- 8.Volkert WA, Hoffman TJ (1999) Chem Rev 99:2269–2292CrossRefGoogle Scholar
- 9.Fettich J, Nair G, Padhy AK, Stare J, Nair N, Moralles R, Tanumihardia M, Riccabona G (2001) IAEA-TECDOC-1228, Vienna, pp 193–198Google Scholar
- 10.Health effects of project shad chemical agent: Phosphorous-32 (Radiotoxic effects) (2004) The Center for Research Information, Inc., Silver Spring. http://www.medresearchnow.com. Spring
- 11.Narendra N (1999) J Nucl Med 40:256–261Google Scholar
- 12.Cyclotron produced radionuclides: principles and practice (2008) IAEA Technical reports series no. 465, VIENNAGoogle Scholar
- 13.Kuznetsov RA, 32,33P-Orthophosphoric acid, A Review on the Current Status and Production Technology of 32,33P-Orthophosphoric acid, KAERI/AR-574/2000, 32/49Google Scholar
- 14.Wierczinski B, Claessens RAMJ, De Goeij JJM, Kolar ZI, Volkers KJ (2001) J Radioanal Nucl Chem 249:279–282CrossRefGoogle Scholar
- 15.Vimalnath KV, Shetty P, Chakraborty S, Das T, Viju C, Sarma HD, Jagadeesan KC, Joshi PV (2013) Cancer Biother Radiopharm 28:423–428CrossRefGoogle Scholar
- 16.Razbash AA, Nerozin NA, Panarin MV, Sevast’yanov YG, Polyakov ON, Podsoblyaev DV, Smetanin WY, Dubinkina TA, Nikulin MP (1991) At Energ 70:333–335CrossRefGoogle Scholar
- 17.Karelin YA, Efimov VN, Filimonov VT, Kuznetsov RA, Revyakin YL, Angreev OI, Zhemkov Y, Bukh VG, Lebedev VM, Spiridonov YN (2000) Appl Radiat Isot 53:825–827CrossRefGoogle Scholar
- 18.Hong YU (2003) JAERI-Conf, JP0350197, pp 230–240Google Scholar
- 19.Ananthakrishnan M (2003) Phosphorous-32 (32P15), manual for reactor produced radioisotopes, Radioisotope Centre, Poland, IAEA TECDOC-1340, pp 158–160Google Scholar
- 20.Ananthakrishnan M, Ramaswamy AN, Nagaraja PS, Kolhe OT (1999) Int. Symp. on Res. React. Util. Saf. and Manag. Lisbon (Portugal), 6–10 Sept 1999, IAEA-SM-360/1PGoogle Scholar
- 21.Chrustowski K (2003) Phosphorous-32 (32P15) (alternate procedure), manual for reactor produced radioisotopes. Radioisotope Centre, Poland, IAEA TECDOC-1340, pp 161–166Google Scholar
- 22.Alanis J, Navarrete JM (2007) J Radioanal Nucl Chem 273:659–662CrossRefGoogle Scholar
- 23.Lima FW, ABRAO A e LT ATALLA (1960) Third Inter-American Symp Peac Appl Nucl Energ Petrópolis, Brazil, 16–23 July, PUBLICAÇÃO I.E.A, NO. 37Google Scholar
- 24.Du M, Knapp FF (2003) Phosphorus-33 (33P15), manual for reactor produced radioisotopes. Radioisotope Centre, Poland, IAEA TECDOC-1340, pp 167–170Google Scholar
- 25.Rahaman MS, Ellis N, Mavinic DS (2008) Water Sci Technol 57:647–654CrossRefGoogle Scholar
- 26.Choudhary VR, Pataskar SG, Pandit MY, Gunjikar VG (1992) Thermochim Acta 194:361–373CrossRefGoogle Scholar
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