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Journal of Radioanalytical and Nuclear Chemistry

, Volume 286, Issue 1, pp 259–263 | Cite as

Study of the cyclotron production of 172Lu: an excellent radiotracer

  • Mahdi SadeghiEmail author
  • Milad Enferadi
  • Hojjat Nadi
Article

Abstract

172Lu due to its suitable (T1/2 = 6.7 days) and high detection sensitivity, is used as a radiotracer in different fields. 172Lu appears to be suitable as a long-lived rare-earth tracer for compound labelling and biodistribution studies. In the present study, excitation functions via 172Yb(p,n)172Lu, natYb(p,xn)172Lu, 172Yb(d,2n)172Lu and natYb(d,xn)172Lu reactions were calculated by ALICE/91, ALICE/ASH and TALYS-1.2 codes. Deposition of natYb2O3 on Cu substrate was carried out via sedimentation method for the production of 172Lu. Cementation separation process and liquid–liquid extraction (LLX) of no-carrier-added (nca) radiolutetium from irradiated ytterbium(III)oxide target hydrochloric solution was described using Na(Hg) amalgam, α-hydroxyisobutyric acid (α-HIB) and di-(2-ethylhexyl)phosphoric acid (HDEHP).

Keywords

172Lu Liquid–liquid extraction Targetry Ytterbium(III)oxide ALICE/ASH 

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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2010

Authors and Affiliations

  1. 1.Agricultural, Medical and Industrial Research SchoolNuclear Science and Technology Research InstituteKaraj, TehranIran
  2. 2.Faculty of Engineering, Research and Science BranchIslamic Azad UniversityTehranIran

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