Journal of Radioanalytical and Nuclear Chemistry

, Volume 283, Issue 2, pp 389–393 | Cite as

Separation of no-carrier-added radioactive scandium from neutron irradiated titanium

  • Tanveer Hussain Bokhari
  • A. Mushtaq
  • Islam Ullah Khan


Production of radioactive scandium by irradiating natural titanium metal in Pakistan Research Reactor-1 was evaluated. The production rate of 47Sc and other radioactive scandium was estimated. High specific activity 47Sc can be produced by irradiating enriched 47Ti in sufficient quantities needed for therapeutic applications. A new separation technique based on column chromatography was developed. Neutron irradiated titanium was dissolved in hydrofluoric acid, which was evaporated and taken in distilled water. The resulting solution was loaded on silica gel column. The radioactive scandium comes out first and the inactive titanium is removed with 2 M HCl. More than 95% radioactive scandium was recovered, while chemical impurity of titanium determined by optical emission spectroscopy was less than 0.01 μg/mL in final product.


Titanium metal target Neutron irradiation No carrier added radioscandium Silica gel column 


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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2009

Authors and Affiliations

  • Tanveer Hussain Bokhari
    • 1
    • 2
  • A. Mushtaq
    • 1
  • Islam Ullah Khan
    • 2
  1. 1.Isotope Production Division, Pakistan Institute of Nuclear Science & TechnologyIslamabadPakistan
  2. 2.Department of ChemistryGovernment College UniversityLahorePakistan

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