Production of no-carrier-added 64Cu and applications to molecular imaging by PET and PETIS as a biomedical tracer
Copper-64 was produced by the 64Ni(p, n)64Cu reaction using enriched 64NiO target. We investigated and compared the production yield of 64Cu for proton beams of various energies by using a thick target. Enriched 64Ni was recovered with high yield by simple procedures. Imaging studies using positron emission tomography (PET) and positron emitting tracer imaging system (PETIS) were performed. We obtained clear images in PET and PETIS studies. The results of this study indicate that 64Cu can be utilized as a biomedical tracer for the molecular imaging both in animals and plants.
KeywordsPositron Emission Tomography Positron Emission Tomography Imaging Proton Beam Thick Target Wide Energy Range
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