Journal of Radioanalytical and Nuclear Chemistry

, Volume 278, Issue 3, pp 575–579 | Cite as

Halogen speciation in the rat thyroid: Simultaneous determination of bromine and iodine by short-term INAA

Biochemistry and Biomedicine

Abstract

The study describes a mode of non-destructive simultaneous determination of bromine and iodine concentrations, by reactor instrumental neutron activation analysis (INAA) in the regime of short-term activation. Under the conditions of 1-minute activation in the neutron flux of 8.0·1013 n·cm−2·s−1, it was possible to determine reliably as little as 5·10−8 g bromine and about 10−7 g iodine in matrices of a given type and of the mass of about 5 mg dry weight. We applied this method for the determination of Br and I concentrations in the whole rat thyroid gland as well as for the halogen speciation in fractions separated from this organ.

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Copyright information

© Springer Science+Business Media, LLC. 2008

Authors and Affiliations

  1. 1.Department of Biochemistry, Faculty of ScienceMasaryk UniversityBrnoCzech Republic
  2. 2.Institute of PhysiologyAcademy of Sciences of the Czech Republic, v.v.i.Prague 4Czech Republic
  3. 3.Institute of Analytical ChemistryAcademy of Sciences of the Czech Republic, v.v.i.Prague 4Czech Republic

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