Journal of Radioanalytical and Nuclear Chemistry

, Volume 266, Issue 2, pp 313–316 | Cite as

Characterization and application of the fac-[188Re(CO)3(H2O)3]+ core

  • Jiaoyun Xia
  • Yongxian Wang
  • Junfeng Yu
  • Jinquan Cao
  • Chunfu Zhang
  • Duanzhi Yin
Article

Summary

Fac-[188Re(CO)3(H2O)3]+ was synthesized with an overall radiochemical yield of 80±5%, and more than 95% radiochemical purity after a QMA Sep-Pak column separation. Fac-[Re(CO)3(H2O)3]+ was also synthesized as a reference sample. The structure of the precursor, fac-[188Re(CO)3(H2O)3]+, was confirmed by high performance of liquid chromatography (HPLC). MN-His (magnetic nanoparticles coated with silica and modified with an amino silane coupling agent, N-[3-(trimethyoxysilyl)propyl]-ethylenediamine (SG-Si900) and immobilized with histidine) was labeled with fac-[188Re(CO)3(H2O)3]+ and an initial animal test of MN-His was conducted for a magnetic targeting study.

Keywords

Silane Liquid Chromatography Histidine Reference Sample Propyl 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag/Akadémiai Kiadó 2005

Authors and Affiliations

  • Jiaoyun Xia
    • 1
  • Yongxian Wang
    • 2
  • Junfeng Yu
    • 3
  • Jinquan Cao
    • 4
  • Chunfu Zhang
    • 5
  • Duanzhi Yin
    • 6
  1. 1.Radiopharmaceutical Research Center, Shanghai Institute of Applied Physics, Graduate School of the Chinese Academy of Sciences
  2. 2.Radiopharmaceutical Research Center, Shanghai Institute of Applied Physics, Graduate School of the Chinese Academy of Sciences
  3. 3.Radiopharmaceutical Research Center, Shanghai Institute of Applied Physics, Graduate School of the Chinese Academy of Sciences
  4. 4.Radiopharmaceutical Research Center, Shanghai Institute of Applied Physics, Graduate School of the Chinese Academy of Sciences
  5. 5.Shanghai Institute of Nuclear ResearchRadiopharmaceutical Research Center, Shanghai Institute of Applied Physics, Graduate School of the Chinese Academy of Sciences
  6. 6.Radiopharmaceutical Research Center, Shanghai Institute of Applied Physics, Graduate School of the Chinese Academy of Sciences

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