Abstract
This paper analyses country-specific determinants of knowledge flows with a view to uncover the role of cross-organizational interactions. Using a sample of some 600,000 patents from the EU27 member states in the period 1990–2007, we take backward citations as dependent variable and find that technological sophistication and research size have a positive effect on knowledge flows. While a national bias towards applied research and development has a negative impact, individual public–private cooperation has a moderating effect due to the generation of scientific knowledge by public institutions. The present study contributes to the debate concerning the direction of R&D investments and provides empirical support to policies aimed at the enhancement of public–private cooperation.
This is a preview of subscription content, log in to check access.


Notes
- 1.
Interestingly, if we include also non-university public research organizations, the share of business funding of R&D in the higher education and government sectors is found to increase in Europe, and is higher than in US (De Backer et al. 2008).
- 2.
Other forms of cooperation encompass private-private and public-public. We focus on public–private cooperation because of its inter-sectoral nature, as opposed to the intra-sectoral style of private-private and of public-public cooperation. In a study on knowledge flows measured by patent citations, inter-sectoral cooperation appears as the most appealing option because it entails accounting for the diversity of attitudes and cultural differences towards openness and intellectual property (Stevens et al. 2013). Actually, in studies about patents the most analysed inter-sectorial co-patenting activity is university-firm patents, which makes sense because it is associated with higher market value (Belderbos et al. 2013). Conversely, public-public co-ownership is very marginal and often subsumed within one category of single-authorship (Callaert et al. 2013).
- 3.
An international consortium of researchers from the University of Newcastle, Incentim (KU Leuven Research and Development), and the Centre for Science and Technology Studies (CWTS) (Leiden University) implemented the data collection.
- 4.
Patents featuring a non-EU27 co-applicant were counted twice. For the econometric analysis, we use as a weight variable the share of number of applicants to avoid double counting.
- 5.
Since we dropped many observations due to missing national data, there may be a bias. We deal with this issue at the end of the results section.
- 6.
To test Hypothesis 1, we tried to include additional national characteristics such as full-time R&D personnel, human resources in science and technology, value of high-tech exports, gross domestic product, etc. We were particularly interested in full-time R&D personnel to closely replicate other works on national innovative capacity (see references in Sect. 2), however, they were excluded because of high multi-collinearity. To test Hypothesis 2, we used share of the sum of higher education plus government expenditure rather than higher education only, which is sensible because in some countries, both are heavily intertwined and the results are similar. However, because we found less theoretical support for this procedure, we prefer to present the results for higher education only. Finally, we tried country fixed effects but they were highly collinear.
- 7.
This specification requires the transformation of the dependent variable nbackcit into log(nbackcit + 1).
References
Almeida, P., & Kogut, B. (1997). The exploration of technological diversity and geographic localization in innovation: start-up firms in the semiconductor industry. Small Business Economics, 9(1), 21–31.
Antonelli, C. (2008). Localised technological change: Towards the economics of complexity. London: Taylor & Francis.
Arrow, K. J. (1962). The economic implications of learning by doing. The Review of Economic Studies, 29(3), 155–173.
Azagra-Caro, J. M. (2014). Determinants of national patent ownership by public research organisations and universities. The Journal of Technology Transfer, 39(6), 898–914.
Azagra-Caro, J. M., Fernández-de-Lucio, I., Perruchas, F., & Mattsson, P. (2009). What do patent examiner inserted citations indicate for a region with low absorptive capacity? Scientometrics, 80(2), 441–455.
Bacchiocchi, E., & Montobbio, F. (2009). Knowledge diffusion from university and public research. A comparison between US, Japan and Europe using patent citations. The Journal of Technology Transfer, 34(2), 169–181.
Balzat, M., & Hanusch, H. (2004). Recent trends in the research on national innovation systems. Journal of Evolutionary Economics, 14(2), 197–210.
Belderbos, R., Cassiman, B., Faems, D., Leten, B., & Van Looy, B. (2013). Co-ownership of intellectual property: Exploring the value-appropriation and value-creation implications of co-patenting with different partners. Research Policy,. doi:10.1016/j.respol.2013.08.013.
Branstetter, L. (1998). Looking for international knowledge spillovers: a review of the literature with suggestion for new approaches. Annales d’Economie et de Statistique, 49–50, 517–540.
Buesa, M., Baumert, T., Heijs, J., & Martínez, M. (2002). Los factores determinantes de la innovación: un análisis econométrico sobre las regiones españolas. Economía Industrial, 347, 67–84.
Callaert, J., Du Plessis, M., Van Looy, B., & Debackere, K. (2013). The impact of academic technology: Do modes of involvement matter? The Flemish Case. Industry and Innovation, 20(5), 456–472.
Callaert, J., van Looy, B., Verbeek, A., Debackere, K., & Thus, B. (2006). Traces of prior art: An analysis of non-patent references found in patent documents. Scientometrics, 69(1), 3–20.
De Backer, K., López-Bassols, V. & Martinez, C. (2008). Open innovation in a global perspective: What do existing data tell us?, OECD Science, Technology and Industry Working Papers, 2008/04, OECD Publishing.
De Bresson, C., & Amesse, F. (1991). Networks of innovators: A review and introduction to the issue. Research Policy, 20(1991), 363–379.
Dinges, M., Berger, M., Frietsch, R., & Kaloudis, A. (2007). Monitoring sector specialisation of public and private funded business research and development. Science and Public Policy, 34(6), 431–443.
Doyle, E., & Connor, F. O. (2013). Innovation capacities in advanced economies: Relative performance of small open economies. Research in International Business and Finance, 27, 106–123.
European Commission (EC, 2002). The Lisbon strategy—Making change happen. Brussels: European Commission COM(2002)14 final.
Fier, H., & Pyka, A. (2014). Against the one-way-street: Analyzing knowledge transfer from industry to science. The Journal of Technology Transfer, 39(2), 219–246.
Fisch, C. O., Hassel, T. M., Sandner, P. G., & Block, J. H. (2014). University patenting: A comparison of 300 leading universities worldwide. The Journal of Technology Transfer. doi:10.1007/s10961-014-9355-x.
Freeman, C. (1987). Technology and economic performance: Lessons from Japan. London: Pinter.
Furman, J. L., & Hayes, R. (2004). Catching up or standing still? National innovative productivity among ‘follower’ countries, 1978–1999. Research Policy, 33, 1329–1354.
Furman, J. L., Porter, M. E., & Stern, S. (2002). The determinants of national innovative capacity. Research Policy, 31, 899–933.
Goldfarb, B. (2008). The effect of government contracting on academic research: Does the source of funding affect scientific output? Research Policy, 37, 41–58.
Griliches, Z. (1992). The search for R&D spillovers. Scandinavian Journal of Economics, 94, 29–47.
Hall, B. H. (2002). The financing of research and development. Oxford Review of Economic Policy, 18(1), 35–51.
Hall, B. H., Jaffe, A., & Trajtenberg, M. (2005). Market value and patent citations. RAND Journal of Economics, 36(1), 16–38.
Harhoff, D., Scherer, F. M., & Vopel, K. (2003). Citations, family size, opposition and the value of patent rights. Research Policy, 32(8), 1343–1363.
Howells, J. (2000). Research and technology outsourcing and systems of innovation. In J. S. Metcalfe & I. Miles (Eds.), Innovation systems in the service economy (pp. 271–295). New York: Springer.
Hu, M. C., & Mathews, J. A. (2005). National innovative capacity in East Asia. Research Policy, 34, 1322–1349.
Hu, M. C., & Mathews, J. A. (2008). China’s national innovative capacity. Research Policy, 37, 1465–1479.
Jaffe, A. B., Trajtenberg, M., & Henderson, R. (1993). Geographic localization of knowledge spillovers as evidenced by patent citations. Quarterly Journal of Economics, 108(3), 577–598.
Kamiyama, S., Sheehan, J. & Martinez, C. (2006). Valuation and exploitation of intellectual property, OECD Science, Technology and Industry Working Papers, 2006/05, OECD Publishing.
Kline, S. J., & Rosenberg, N. (1986). An overview of innovation. In R. Landau & N. Rosenberg (Eds.), The positive sum strategy: Harnessing technology for economic growth. Washington: National Academy Press.
Lecocq, C., Song, X., Vereyen, C., Du Plessis, M., & Van Looy, B. (2008). Data production methods for harmonized patent statistics: Regionalizing patent data—EU-27: Methodological outline. Sogeti-Incentim, mimeo.
Mansfield, E. (1998). Academic research and industrial innovation: An update of empirical findings. Research Policy, 26(7), 773–776.
Narin, F., Hamilton, K. S., & Olivastro, D. (1997). The increasing linkage between US technology and public science. Research Policy, 26(3), 317–330.
Nelson, R. R. (1959). The simple economics of basic scientific research. Journal of Political Economy, 67(3), 297–306.
Nonaka, I. (1994). A dynamic theory of organizational knowledge creation. Organization Science, 5(1), 14–37.
OECD. (1998). Technology, productivity and job creation: Best policy practices. Paris: OECD.
Porter, M. E. (1990). New global strategies for competitive advantage. Strategy & Leadership, 18(3), 4–14.
Quatraro, F., & Usai, F. (2014). Are knowledge flows all alike? Evidence from European regions. Contributi di Ricerca CRENoS, 2014/05. Centre for North South Economic Research, University of Cagliari and Sassari, Sardinia.
Roach, M., & Cohen, W. M. (2013). Lens or prism? Patent citations as a measure of knowledge flows from public research. Management Science, 59(2), 504–525.
Romer, P. M. (1990). Endogenous technological change. Journal of Political Economy, 98(5), S71–S102.
Saint-George, M., & van Pottelsberghe de la Potterie, B. (2013). A quality index for patent systems. Research Policy, 42, 704–719.
Sapir, A. (chairman) (2003). An agenda for a growing Europe: Making the EU economic system deliver. Report of an independent high level study group established on the initiative of the president of the European Commission.
Schartinger, D., Rammer, C., Fischer, M. M., & Frölich, J. (2002). Knowledge interactions between universities and industry in Austria: Sectoral patterns and determinants. Research Policy, 31, 303–328.
Stevens, H., Van Overwalle, G., Van Looy, B., & Huys, I. (2013). Perspectives and opportunities for precompetitive public–private partnerships in the biomedical sector. Biotechnology Law Report, 32(3), 131–139.
Tijssen, R. J. W. (2001). Global and domestic utilization of industrial relevant science: Patent citation analysis of science-technology interactions and knowledge flows. Research Policy, 30, 35–54.
Van Looy, B., Ranga, M., Callaert, J., Debackere, K., & Zimmermann, E. (2004). Combining entrepreneurial and scientific performance in academia: Towards a compounded and reciprocal Matthew-effect? Research Policy, 33, 425–441.
Wallsten, S. J. (2000). The effects of government-industry R&D programs on private R&D: The case of the small business innovation research program. RAND Journal of Economics, 31(1), 82–100.
Yang, H., Phelps, C., & Steensma, H. K. (2010). Learning from what others have learned from you: The effects of knowledge spillovers on originating firms. Academy of Management Journal, 53(2), 371–389.
Acknowledgments
Marina Ranga participated in the brainstorming that led to this paper and the thorough revision of an earlier version. Catalina Martínez provided us with data to update the database. Both reviewed a previous version of the manuscript. Anabel Fernández-Mesa, Alberto Marzucchi and Francesco Rentocchini helped with the econometric estimations. Richard Woolley shared insights on the structural composition of research expenditure. Elena M. Tur and François Perruchas offered technical assistance. The research was carried out with funding from project GV/2012/018 of the Valencian Regional Government. Previous versions of the paper were presented at the 2013 Eu-SPRI Forum Conference, the 2013 ISSI Conference and the 2013 IPTS Workshop on ‘Harnessing the Powers of Patent Data’. The authors acknowledge helpful comments from the audiences, especially Jorge Niosi and Julio Raffo. Joaquín M. Azagra-Caro is grateful to René van Bavel and Xabier Goenaga for their institutional support, and to the international consortium that produced the database, especially Henry Etzkowitz, Marina Ranga and members of Incentim and CWTS, led, respectively, by Bart Van Looy and Robert J.W. Tijssen.
Author information
Additional information
The initial data construction was conducted within ERAWATCH, a joint initiative of the European Commission’s Directorate General for Research and the Joint Research Centre—Institute for Prospective Technological Studies. The views expressed in this article are those of the author and do not necessarily reflect those of the European Commission. Neither the European Commission nor anyone acting on its behalf is responsible for the use that might be made of the information.
Rights and permissions
About this article
Cite this article
Azagra-Caro, J.M., Consoli, D. Knowledge flows, the influence of national R&D structure and the moderating role of public–private cooperation. J Technol Transf 41, 152–172 (2016). https://doi.org/10.1007/s10961-014-9382-7
Published:
Issue Date:
Keywords
- Knowledge flows
- National innovative capacity
- Patents
- Citations
JEL Classification
- O31
- O33
- O34