Association Between TG-to-HDL-C Ratio and In-Stent Stenosis Under Optical Coherence Tomography Guidance
- 52 Downloads
We determined the relevance between the TG-to-HDL-C ratio and stent restenosis. Ninety-nine patients with in-stent stenosis (ISR) who were admitted to An Zhen Hospital in Beijing between April 2014 and June 2017 were selected. At the same time, 122 patients with coronary stenosis <50% were selected. All patients were tested for TG, HDL-C, and TG/HDL-C ratio. Optical coherence tomography (OCT) can assess microscopic status in all ISR patients. The proportion of male and Diabetic patients were significantly higher for ISR. There were differences in the prevalence of cigarette smokers among the different tissue types, among which the layered tissue type accounted for the highest proportion. In logistic regression analysis the study showed that male, diabetes mellitus, and the TG/HDL-C ratio are risk factors for ISR. The ISR ROC was 0.725 based on the TG/HDL-C ratio diagnosis. It is related to the degree of coronary stenosis and effective in diagnosing in-stent stenosis in ISR.
KeywordsOptical coherence tomography Coronary heart disease In-stent restenosis TG-to-HDL ratio
Compliance with Ethical Standards
Conflict of Interest
The Institutional Ethics Committee of Beijing An Zhen Hospital approved the research protocol (No.2018022X).
- 5.Shim, Y. S., Baek, J. W., Kang, M. J. et al., Reference Values for The Triglyceride to High-Density Lipoprotein Cholesterol Ratio and Non-High-Density Lipoprotein Cholesterol in Korean Children and Adolescents: The Korean National Health and Nutrition Examination Surveys 2007–2013. J. Atheroscler. Thrombosis. 23(12):1334–1344, 2016.CrossRefGoogle Scholar
- 9.Yokoyama, K., Tani, S., Matsuo, R. et al., Increased triglyceride/high-density lipoprotein cholesterol ratio may be associated with reduction in the low-density lipoprotein particle size: Assessment of atherosclerotic cardiovascular disease risk. Heart Vessels, 2018. https://doi.org/10.1007/s00380-018-1247-9.
- 14.Kwon, Y.-J., Park, J.-W., Lim, H.-J. et al., Triglyceride to high density lipoprotein cholesterol ratio and its association with periodontal disease in Korean adults: Findings based on the 2012–2014 Korean national health and nutrition examination survey. Clin. Oral Investig. 5:1–8, 2017.Google Scholar
- 22.Nagai, H., Ishibashi-ueda, H., and Fujll, K., Histology of highly echolucent regions in optial coherence tomography images from two patients with sirolimus eluting stent restenosis. Catheter Cardiovasc. Interv. 75:961–963, 2010.Google Scholar
- 27.Tada, T., Kadota, K., Hosogi, S. et al., Association between tissue characteristics assessed with optical coherence tomography and mid-term results after percutaneous coronary intervention for in-stent restenosis. Lesions: a comparison between balloon angioplasty, paclitaxel-coated balloon dilatation, and drug-eluting stent implantation. Eur. Heart J. Cardiovasc. Imag. 16(10):1101–1111, 2015.CrossRefGoogle Scholar