Two New Dy(III) and Cu(II) Coordination Polymers: Crystal Structures and Anti-liver Cancer Activity

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Abstract

Two new three-dimensional coordination polymers (H2NMe2)[Dy43−OH)4(NMF)3(H2O)(L1)3](H2O)2 (1, NMF = N-methylformamide, H3L1 = 3,5-bis(4-(1H-tetrazol-5-yl)phenoxy)benzoic acid) and [Cu(L2)2(H2O)](H2O)2 (2, H2L2 = 4-(4-pyridyl)-isophthalic acid) have been successfully prepared using two N,O-mixed donor organic ligands. The structures of these complexes have been successfully determined by single crystal X-ray diffraction. In addition, in vitro antitumor activity of compounds 1 and 2 on four human liver cancer cells (SMMC7721, Bel-7402, MHCC97 and HCCLM3) was further determined and the results show that the two compounds showed promising activity.

Keywords

Coordination polymers X-ray diffraction Liver cancer 

Notes

Acknowledgements

This work was supported by grants from the The Natural Science Foundation of Inner Mongolia [2017MS(LH)0819].

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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Inner Mongolia University for NationalitiesTongliaoChina
  2. 2.The First Affiliated Hospital of Inner Mongolia University for NationalitiesTongliaoChina

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