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Cardiovascular Risk Assessment Varies Widely by Calculator and Race/Ethnicity in a Majority Latinx Cohort Living with HIV

  • Yuanyuan Liang
  • Norma S. Ketchum
  • Barbara J. Turner
  • John Flores
  • Delia Bullock
  • Roberto Villarreal
  • Polly H. Noël
  • Michael T. Yin
  • Barbara S. TaylorEmail author
Original Paper
  • 30 Downloads

Abstract

Comparison of cardiovascular disease (CVD) risk calculators in Latinx majority populations living with HIV can assist clinicians in selecting a calculator and interpreting results. 10-year CVD risks were estimated for 652 patients seen ≥ 2 times over 12 months in a public clinic using three risk calculators: Atherosclerotic CVD risk Calculator (ASCVD), Framingham Risk Calculator (FRC), and Data Collection on Adverse Effects of Anti-HIV Drugs Study (D:A:D) Calculator. Median estimated 10-year CVD risk in this population was highest using FRC (11%), followed by D:A:D (10%), and lowest with ASCVD (5%; p < 0.001). However, D:A:D classified 44.3% in a high/very high risk category compared to FRC (20.7%) and ASCVD (33.4%) (all p < 0.001). ASCVD risk estimates differed significantly by race/ethnicity (p < 0.001). Risk varied widely across three risk calculators and by race/ethnicity, and providers should be aware of these differences when choosing a calculator for use in majority minority populations.

Keywords

HIV Cardiovascular risk Cardiovascular risk calculation Race Ethnicity Hispanic 

Notes

Acknowledgements

This study was funded by an American Heart Association grant to BT. The authors wish to gratefully acknowledge the staff and providers at the FFACTS clinic and the research administration of the University Health System for their support of this investigation.

Funding

This study was funded by the American Heart Association (Grant No. 14CRP20150023).

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Yuanyuan Liang
    • 1
  • Norma S. Ketchum
    • 2
  • Barbara J. Turner
    • 3
    • 5
  • John Flores
    • 4
  • Delia Bullock
    • 5
  • Roberto Villarreal
    • 6
  • Polly H. Noël
    • 7
  • Michael T. Yin
    • 8
  • Barbara S. Taylor
    • 3
    • 5
    Email author
  1. 1.Department of Epidemiology and Public HealthUniversity of Maryland School of MedicineBaltimoreUSA
  2. 2.Department of Epidemiology and BiostatisticsUT Health San AntonioSan AntonioUSA
  3. 3.Research to Advance Community Health (ReACH) CenterUT Health San AntonioSan AntonioUSA
  4. 4.Joint Residency Program in Medicine and PediatricsUniversity of Illinois at Chicago College of MedicineChicagoUSA
  5. 5.Department of MedicineUT Health San AntonioSan AntonioUSA
  6. 6.Research and Information ManagementUniversity Health SystemSan AntonioUSA
  7. 7.Department of Family & Community MedicineUT Health San AntonioSan AntonioUSA
  8. 8.Department of MedicineColumbia University College of Physicians and SurgeonsNew YorkUSA

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