Treatment Adherence, Meaning in Life and Affects in Quality of Life of HIV/AIDS Patients

  • Ana ReisEmail author
  • Leonor Lencastre
  • Catherina Jonsson
  • Marina Prista GuerraEmail author
Research Paper


The objective of this study is to identify the predictors of the QOL’s domains, specifically, to understand the relationship between biological markers, psychological variables and QOL of HIV/AIDS patients. Cross-sectional developed with 94 individuals with HIV/AIDS, who attend the outpatient clinic specialty and have had an antiretroviral prescription for 3 months. WHOQOL-Bref (QOL), CEAT-VIH (treatment adherence), Meaning in life scale (ML) and PANAS (affects), and sociodemographic and clinical questionnaire. The results of the predictive models of the QOL’s domains, when controlling for the viral load and the CD4 + T cell count, encompass affect balance, treatment adherence and meaning in life with the highest explained variance in the predictive models of QOL in physical 37.4% and psychological 33.9% domains. The affect balance is a predictor of all QOL’s domains and treatment adherence is a predictor of three of them. ML is a predictor of the psychological and environmental domains. This study emphasizes the importance of affect balance, treatment adherence and meaning in life for the QOL in HIV.


Quality of life Treatment adherence Meaning in life Affect balance HIV/AIDS 



We wish to thank all the patients who made this study possible.


This work was funded by the Center for Psychology at the University of Porto, Portuguese Science Foundation (FCT UID/PSI/00050/2019).


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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Escola Superior de Saúde de Santa MariaPortoPortugal
  2. 2.Faculdade de Psicologia e de Ciências da Educação da Universidade do PortoPortoPortugal
  3. 3.Centre for Psychology of University of PortoPortoPortugal

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