Journal of Genetic Counseling

, Volume 17, Issue 4, pp 351–364

Testicular Cancer and Genetics Knowledge Among Familial Testicular Cancer Family Members

  • June A. Peters
  • Ellen B. Beckjord
  • Deliya R. Banda Ryan
  • Ann G. Carr
  • Susan T. Vadaparampil
  • Jennifer T. Loud
  • Larissa Korde
  • Mark H. Greene
Original Research

Abstract

Purpose

It was our aim to determine baseline levels of testicular cancer and genetics knowledge among members of families with Familial Testicular Cancer (FTC).

Methods

This is a sub-study of an ongoing National Cancer Institute (NCI) multidisciplinary, etiologically-focused, cross-sectional study of FTC. We evaluated 258 male and female participants including testicular cancer (TC) survivors, blood relatives and spouses to assess factors associated with a Genetic Knowledge Scale (GKS) and Testicular Cancer Knowledge Scale (TCKS).

Results

Knowledge levels were generally low, with genetic knowledge lower than TC knowledge (p < 0.01). Men with a personal TC history scored highest on TC knowledge, while gender, age and education differentially influenced knowledge levels, particularly among unaffected relatives.

Conclusions

Prior to identifying FTC susceptibility genes, we recommend tailoring FTC genetic education to the different informational needs of TC survivors, their spouses and relatives, in preparation for the day when clinical susceptibility testing may be available.

Keywords

Testicular cancer Knowledge Genetic counseling Genetic education Familial Hereditary 

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Copyright information

© National Society of Genetic Counselors, Inc. 2008

Authors and Affiliations

  • June A. Peters
    • 1
  • Ellen B. Beckjord
    • 2
  • Deliya R. Banda Ryan
    • 1
  • Ann G. Carr
    • 3
  • Susan T. Vadaparampil
    • 4
  • Jennifer T. Loud
    • 1
  • Larissa Korde
    • 1
  • Mark H. Greene
    • 1
  1. 1.Clinical Genetics Branch (CGB), Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), National Institutes of Health (NIH)Department of Health and Human Services (DHHS)RockvilleUSA
  2. 2.RAND CorporationPittsburghUSA
  3. 3.WestatRockvilleUSA
  4. 4.Health Outcomes and Behavior ProgramMoffitt Cancer CenterTampaUSA

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