Proteinous Polymeric Shell Decorated Nanocrystals for the Recognition of Immunoglobulin M

  • Sibel Büyüktiryaki
  • Filiz Yılmaz
  • Rıdvan Say
  • Arzu ErsözEmail author


This study demonstrates the preparation of photosensitively orientated and crosslinked proteinous polymeric shell having quantum dot based nanocrystals through Amino acid Decorated and Light Underpinning Conjugation Approach (ANADOLUCA). ANADOLUCA is based on photo-electron transfer method and uses these decorated nanocrystals for specifically and effectively recognition and detection of Immunoglobulin M in the aqueous environment. The conjugation method effectively provides an orientation of affinity pairs on the surface of quantum dots nanocrystals. This photosensitive ruthenium-based amino acid monomer is a synthetic and inexpensive material for the preparation of bioconjugates. The nanocrystals give advantages for using a wide pH and temperature range. The construction and preparation method is applicable to silica materials, superparamagnetic particles, quantum dots, carbon nanotubes, Ag/Au nanoparticles, Au surfaces, and polymeric materials. This prepared proteinous polymeric shell decorated nanocrystals are of great potential in applications in life sciences and can be used in infection case studies or allergy symptoms.


Orientated conjugation Recognition of IgM ANADOLUCA method Quantum dots Photosensitive crosslinking 


Compliance with Ethical Standards

Conflict of Interest

The authors declare that there is no conflict of interest regarding the publication of this manuscript.

Financial Interests

The authors declare no competing financial interest.


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Sibel Büyüktiryaki
    • 1
  • Filiz Yılmaz
    • 2
  • Rıdvan Say
    • 3
    • 4
  • Arzu Ersöz
    • 2
    • 4
    • 5
    Email author
  1. 1.Yunusemre Vocational SchoolAnadolu UniversityEskisehirTurkey
  2. 2.Department of ChemistryEskişehir Technical UniversityEskisehirTurkey
  3. 3.Department of ChemistryAnadolu UniversityEskisehirTurkey
  4. 4.Bionkit Co Ltd.Anadolu University TeknoparkEskisehirTurkey
  5. 5.Fen Fakültesi, Kimya BölümüEskişehir Teknik UniversitesiEskişehirTurkey

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