A Smart Fluorescent Probe Based on Salicylaldehyde Schiff’s Base with AIE and ESIPT Characteristics for the Detections of N2H4 and ClO

  • Ya Xie
  • Liqiang YanEmail author
  • Yujian Tang
  • Minghui Tang
  • Shaoyang Wang
  • Li Bi
  • Wanying Sun
  • Jianping Li


Smart and versatile salicylaldehyde Schiff’s bases have been proved their excellent performances including large shocks shift, dual emission wavelengths and sensitive to environment for fluorescence analysis. Herein, a simple salicylaldehyde Schiff’s base molecular (PBAS) with aggregation-induced emission (AIE) and the excited-state intramolecular proton-transfer (ESIPT) effects was constructed for detecting N2H4 and ClO. The highly specific and sensitive response to N2H4 was witnessed by the fast turn-on of the strong blue fluorescence and to ClO was observed by the rapid turn off of the weak green fluorescence simultaneous decomposing of the probe. The results of mass spectrum analysis showed that probe PBAS decomposed under the influence of N2H4, whereas probe PBAS can complex with ClO and prevent effective ESIPT process. Benefiting from its high properties, this fluorescence molecular provides an effective tool for probing N2H4 and ClO in live cells.


Fluorescence probe N2H4 ClO Salicylaldehyde Schiff’s bases 



This work was supported by College students’ innovation and entrepreneurship training program (201810596130), the Natural Science Foundation of Guangxi Province of China (Project No.2015GXNSFFA139005) and High Level Innovation Teams of Guangxi Colleges & Universities and Outstanding Scholars Program (Guijiaoren [2014]49).

Supplementary material

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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.College of Chemistry and BioengineeringGuilin University of TechnologyGuilinPeople’s Republic of China
  2. 2.Guangxi Key Laboratory of Electrochemical and Magnetochemical Functional MaterialsGuangxi Colleges and Universities Key Laboratory of Food Safety and DetectionGuilinPeople’s Republic of China

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