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Template Synthesis, Spectral, Thermal and Glucose Sensing of Pr3+ Complexes of Metformin Schiff-Bases

  • Marwa Mahmoud
  • Enas Abdel-Salam
  • Mahmoud Abou-Elmagd
  • Shehab SallamEmail author
FLUORESCENCE NEWS ARTICLE
  • 34 Downloads

Abstract

Schiff-bases of metformin with each of salicylaldehyde (HL1); 2,3-dihydroxybenzaldehyde (H2L2); 2,4-dihydroxybenzaldehyde (H2L3); 2,5-dihydroxybenzaldehyde (H2L4); 3,4-dihydroxybenzaldehyde (H2L5) and 2-hydroxynaphthaldehyde (HL6) and their complexes with Pr(III) were synthesized by template reaction. The complexes were characterized through elemental analysis, conductivity and magnetic moment measurements, IR, UV-Vis., fluorescence, GC-MS and XRD spectroscopy. The complexes exhibit a series of characteristic emission bands for Pr3+ ion in the 481-472 and 590-580 nm range with a 318-332 nm excitation source. The complexes have eight coordinated structure with the formulae [PrL1-4,6(NO3)2(H2O)3].nH2O where n = 1, 1½, 3, 4, 4 and [PrL5(NO3)(H2O)5].2H2O. The suggested stereochemistry was confirmed using TGA, DTG and DTA analysis and a mechanism for thermal decomposition was proposed. Coates-Redfern equation was used to calculate kinetic and thermodynamic parameters of the main decomposition step. The utility of the complexes towards the detection of glucose at physiologically relevant pH in phosphate buffer using UV-Vis and fluorescence spectroscopy as well as viscosity measurements are tried where the association constants were calculated.

Graphical Abstract

Keywords

Metformin Schiff-bases Pr(III) complexes Spectral and thermal properties Glucose sensing 

Notes

Supplementary material

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Science and Mathematics Engineering, Faculty of Petroleum and Mining EngineeringSuez UniversitySuezEgypt
  2. 2.Department of Chemistry, Faculty of ScienceSuez Canal UniversityIsmailiaEgypt
  3. 3.Holding Company for Water & WastewaterIsmailiaEgypt

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