Journal of Fluorescence

, Volume 17, Issue 2, pp 127–131

Metal Enhanced Fluorescence Solution-based Sensing Platform 2: Fluorescent Core-Shell Ag@SiO2 Nanoballs

  • Kadir Aslan
  • Meng Wu
  • Joseph R. Lakowicz
  • Chris D. Geddes
Short Communication

Abstract

In this Rapid Communication, we present the development of monodisperse core-shell (silver core-silica shell) nanoparticles with various shell thicknesses featuring a fluorophore, subsequently named Metal-Enhanced Fluorescence (MEF) nanoballs. MEF nanoballs consist of a ≈130 nm silver nanoparticle core, a silica shell with up to 35 nm thickness and fluorophores doped within the silica shell. Fluorescent nanobubbles where the silver core is removed by chemical etching are used as control samples to show the benefits of using silver nanoparticles, i.e, Metal-Enhanced Fluorescence. Finally, we demonstrate the broad potential biological applications of MEF nanoballs by employing near-infra red emitting probes (Rhodamine 800) within the silica shell, for potential applications in cellular imaging and solution-based sensing.

Keywords

Metal-enhanced fluorescence Radiative decay engineering Plasmon enhanced luminescence Plasmon enhanced fluorescence Surface enhanced fluorescence Fluorescence Plasmon Plasmonics Nanoparticles Silver nanoparticles Silver colloids Solution sensing platform 

Symbol and acronyms

Ag@SiO2

Silver core, silica shell nanoparticles

MEF

Metal-Enhanced Fluorescence

SPR

Surface Plasmon Resonance

Rh800

Rhodamine 800

TEM

Transmission Electron Microscope

TEOS

Tetraethyl orthosilicate

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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Kadir Aslan
    • 1
  • Meng Wu
    • 2
  • Joseph R. Lakowicz
    • 2
  • Chris D. Geddes
    • 1
    • 2
  1. 1.Institute of Fluorescence, Laboratory for Advanced Medical Plasmonics, Medical Biotechnology CenterUniversity of Maryland Biotechnology InstituteBaltimoreUSA
  2. 2.Center for Fluorescence SpectroscopyUniversity of Maryland School of MedicineBaltimoreUSA

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