Psychiatric Symptoms and Quality of Life in Patients Affected by Epidermolysis Bullosa

  • Francesco Margari
  • Paola A. Lecce
  • Wanda Santamato
  • Patrizia Ventura
  • Nicola Sportelli
  • Giuseppina Annicchiarico
  • Ernesto Bonifazi
Article

Abstract

The aim of our study was to provide a psychosocial and psychiatric evaluation of patients with epidermolysis bullosa (EB; a rare genetic disorder characterized by skin fragility), to assess psychological status, ascertain the presence of any psychiatric disorders and understand the impact of EB on quality of life. Twenty-five patients were assessed using a case record form and several standardized instruments. In 82% of patients, EB had a negative impact on quality of life and 80% of patients experienced psychiatric symptoms. Our findings revealed a high prevalence of psychosocial problems and psychiatric symptoms in patients with EB and suggested that a combined bio-psychosocial approach is the most appropriate therapeutic intervention.

Keywords

Epidermolysis bullosa Psychiatric aspects Quality of life Rare disorders 

Notes

Acknowledgments

We gratefully acknowledge the support of the Pediatric Dermatology Association of Bari (http://www.dermatologiapediatrica.com).

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Francesco Margari
    • 1
  • Paola A. Lecce
    • 1
  • Wanda Santamato
    • 1
  • Patrizia Ventura
    • 1
  • Nicola Sportelli
    • 1
  • Giuseppina Annicchiarico
    • 2
  • Ernesto Bonifazi
    • 2
  1. 1.Department of Neurologic and Psychiatric SciencesUniversity of BariBariItaly
  2. 2.Pediatric Dermatology Unit PoliclinicoUniversity of BariBariItaly

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