Journal of Combinatorial Optimization

, Volume 10, Issue 1, pp 23–39 | Cite as

Novel Approaches for Analyzing Biological Networks

  • Balabhaskar BalasundaramEmail author
  • Sergiy Butenko
  • Svyatoslav Trukhanov


This paper proposes clique relaxations to identify clusters in biological networks. In particular, the maximum n-clique and maximum n-club problems on an arbitrary graph are introduced and their recognition versions are shown to be NP-complete. In addition, integer programming formulations are proposed and the results of sample numerical experiments performed on biological networks are reported.


n-cliques n-clubs clique relaxations social networks biological networks 


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Copyright information

© Springer Science + Business Media, Inc. 2005

Authors and Affiliations

  • Balabhaskar Balasundaram
    • 1
    Email author
  • Sergiy Butenko
    • 1
  • Svyatoslav Trukhanov
    • 1
  1. 1.Department of Industrial EngineeringTexas A&M UniversityUSA

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