Journal of Clinical Monitoring and Computing

, Volume 27, Issue 4, pp 385–393 | Cite as

The use of heart rate variability for the early detection of treatable complications after aneurysmal subarachnoid hemorrhage

  • Soojin Park
  • Farhad Kaffashi
  • Kenneth A. Loparo
  • Frank J. Jacono
Original Paper


High-grade aneurysmal subarachnoid hemorrhage patients are monitored in the ICU for up to 21 days, as they are at risk for complications such as vasospasm of cerebral arteries, cardiac arrhythmias and neurogenic stress cardiomyopathy. The diagnosis of these treatable complications is often delayed by the limitations of monitoring capabilities. We applied computational analysis to a cohort of 24 aneurysmal subarachnoid hemorrhage patients, to identify heart rate variability and ECG frequency profiles that may be potential biomarkers of severe vasospasm, reversible cardiomyopathy and death.


Computational analysis of heart rate variability Heart rate variability Intensive care monitoring 


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Soojin Park
    • 1
  • Farhad Kaffashi
    • 2
  • Kenneth A. Loparo
    • 2
  • Frank J. Jacono
    • 3
  1. 1.Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaUSA
  2. 2.Department of Engineering and Computer ScienceCase Western Reserve UniversityClevelandUSA
  3. 3.Division of Pulmonary, Critical Care and Sleep MedicineCase Western Reserve University School of MedicineClevelandUSA

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