Journal of Clinical Monitoring and Computing

, Volume 22, Issue 6, pp 391–400 | Cite as

Therapeutic control of the circulation

  • William Geoffrey Parkin
  • Mark Stephen Leaning


By regarding the circulation from the perspective of the venous return, continuous therapeutic control of the mean arterial blood pressure, cardiac output and tissue oxygen flow can be seen to be the consequence of a series of equations based on conventionally measured variables. This approach permits a graphical solution to circulation guidance, open or closed loop control and goal directed therapy of broad general applicability.

Key words

circulation therapeutic control haemodynamics oxygen delivery clinical guidance system, clinical decision support clinical decision support 


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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • William Geoffrey Parkin
    • 1
    • 2
    • 3
  • Mark Stephen Leaning
    • 1
  1. 1.Applied Physiology Pty LtdSydneyAustralia
  2. 2.Monash Medical CentreMelbourneAustralia
  3. 3.Crows NestAustralia

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