Clinically Pertinent Manganese Oxide/Polyoxytyramine/Reduced Graphene Oxide Nanocomposite for Voltammetric Detection of Salivary and Urinary Arsenic

  • Sathish Kumar Ponnaiah
  • Prakash PeriakaruppanEmail author
  • Mohannivas Selvam
  • Saravanan Muthupandian
  • B. Jeyaprabha
  • Rayappan Selvanathan
Original Paper


Arsenic (AsIII), a notorious environmental hazard poses threat to the lives of several hundred million people. Notwithstanding radical developments of AsIII detection in water, a fast, simple and sensitive electrochemical process with lower detection limit for the quantification of AsIII in saliva and urine samples has scarcely ever been tried. Here, we have detected the poisoning due to AsIII in the saliva and urine samples of tobacco-chewers/smokers using a novel one-pot synthesized MnO2/polyoxytyramine/rGO nanocomposite. The composite was characterized by various analytical techniques such as UV–Vis. and FT-IR spectroscopic analyses, XRD, SEM, TEM, EDAX and elemental mapping analyses. The proposed AsIII quantification system has a wide linearity range (0.01–0.900 ppb) and the lowest detection limit (42 parts per trillion).


Nanocomposite MnO2/polyoxytyramine/rGO Voltammetry Arsenic quantification Saliva and urine samples 



The “Catalyzed and Financial support” by Tamilnadu State Council for Science and Technology, Department of Higher Education, Government of Tamilnadu, India for the award of research funding for research scholars (RFRS) scheme (TNSCST/RFRS/VR/07/2018-19) is very much acknowledged.

Supplementary material

10876_2019_1696_MOESM1_ESM.docx (923 kb)
Supplementary material 1 (DOCX 922 kb)


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of ChemistryThiagarajar CollegeMaduraiIndia
  2. 2.Department of Microbiology and Immunology, Institute of Biomedical Sciences, College of Health ScienceMekelle UniversityMekelleEthiopia
  3. 3.Department of Civil EngineeringSethu Institute of TechnologyVirudhunagarIndia
  4. 4.Department of ChemistryArul Anandar CollegeKarumathurIndia

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