Structural Physico Chemical Studies and Biological Analyses of a Cadmium Cluster Complex
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The decachlorocadmate (II) cluster templated with homopiperazinium cation (C5H14N2)2[Cd3Cl10]·4H2O has been grown using the slow evaporation method and characterized by X-ray diffraction, FTIR, Raman, 1H and 13C-NMR spectroscopies. Thermal investigations have also been made for the title compound. The X-ray structural analysis has elucidated the different inter-contacts in the crystal structure between the [Cd3Cl10]4− clusters, the water molecules and homopiperazinium entities stabilizing the 3D-supramolecular structure. These thermal investigations have also revealed a double dehydration phenomenon at around 96 and 125 °C. The TG curve shows that the compound is stable up to the decomposition temperature of around 317 °C. The title compound has been tested for its in vitro antioxidant and antibacterial activities. The 1,1-diphenyl-2-picrylhydrazil (DPPH) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) test has shown that the compound synthesized is characterized by a significant antioxidant activity when compared to ascorbic acid and that it is active against all the tested bacteria. Nevertheless, bacteria sensitivity depends on the bacterial membrane structure. Indeed gram-negative bacteria are more sensitive to the compound tested than the gram-positive ones.
KeywordsDecachlorocadmate Crystal structure Thermal investigation Antioxidant activity Antibacterial activity
The authors gratefully acknowledge the support of the Tunisian Ministry of Higher Education and Scientific Research and the technical help for the X-ray data collection rendered by N. Chniba-Boudjada, Professor at CNRS, Institut Neel, Grenoble.
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