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Journal of Cluster Science

, Volume 25, Issue 5, pp 1389–1399 | Cite as

Microwave-Assisted One-Pot Synthesis of Octahydroquinazolinone Derivatives Using Molybdenum Oxide Nanoparticles in Solvent-Free Condition

  • Sunita Jadhav
  • Priyanka L. Anandgaonker
  • Ganesh Kulkarni
  • Suresh T. Gaikwad
  • Anjali S. RajbhojEmail author
Original Paper

Abstract

Molybdenum oxide nanoparticle has been shown to be an inexpensive, efficient and mild catalyst for the one-pot synthesis of octahydroquinazolinone derivatives using dimedone, urea/thiourea and appropriate aromatic aldehydes under microwave-irradiation. Molybdenum oxide nanoparticles were prepared by electrochemical reduction method in which parameters such as current density, solvent polarity, distance between electrodes, and concentration of stabilizers are used to control the size of nanoparticles.

Graphical Abstract

Molybdenum oxide nanoparticle has been shown to be an inexpensive, efficient and mild catalyst for the one-pot synthesis of octahydroquinazolinone derivatives using dimedone, urea/thiourea and appropriate aromatic aldehydes under microwave-irradiation.

Keywords

Molybdenum oxide nanoparticles Biginelli reaction Octahydroquinazolinone derivatives Microwave-irradiation 

Notes

Acknowledgments

The authors are grateful to the Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad and UGC-SAP-DRS-1 scheme New Delhi for providing the laboratory facility. One of the author (ASR) is thankful for financial assistance from UGC Major Research Project, New Delhi.

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Sunita Jadhav
    • 1
  • Priyanka L. Anandgaonker
    • 1
  • Ganesh Kulkarni
    • 1
  • Suresh T. Gaikwad
    • 1
  • Anjali S. Rajbhoj
    • 1
    Email author
  1. 1.Department of ChemistryDr. Babasaheb Ambedkar Marathwada UniversityAurangabadIndia

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