Journal of Chemical Crystallography

, Volume 37, Issue 11, pp 733–738

Synthesis, Characterization and Structural Conformation Studies of 2-Amino-3-ethoxycarbonyl-4-(4′-methoxy Phenyl)-4H-pyrano-[3,2-c]-chromene-6-methyl-5-one

  • S. Naveen
  • S. Lakshmi
  • Dinesh Manvar
  • Alpesh Parecha
  • Anamik Shah
  • M. Anandalwar Sridhar
  • J. Shashidhara Prasad
Original Paper

Abstract

2-amino-3-ethoxycarbonyl-4-(4′-methoxy Phenyl)-4H-pyrano-[3,2-c]-chromene-6-methyl-5-one was synthesized by the two-component reaction of 6-methyl-4-hydroxy coumarin with 4′-methoxy-2-cyano cinnamate, which was synthesized by Knoevenagel reaction with 88% yield. The compound obtained was characterized by spectroscopic techniques and confirmed by X-ray crystallographic studies. The crystallographic data analysis reveals that the title compound crystallizes in the triclinic space group \(P\overline{1}\) with cell parameters a = 7.7750(8) Å, b = 9.0310(6) Å, c = 15.6120(17) Å, α = 77.249(7)°, β = 115.860(3)°, γ = 70.139(7)°, V = 1,003.0(16) Å3 for Z = 4. The structure has been solved by direct methods and refined to R1 = 0.0552 for 3,164 observed reflections with I > 2 σ(I). The pyran ring is in a flattened boat conformation. The carbonyl group is oriented in a -synperiplanar(cis) conformation.

Keywords

Knoevenagel reaction Crystal structure Flattened boat Hydrogen bonds 

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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • S. Naveen
    • 1
  • S. Lakshmi
    • 1
  • Dinesh Manvar
    • 2
  • Alpesh Parecha
    • 2
  • Anamik Shah
    • 2
  • M. Anandalwar Sridhar
    • 1
  • J. Shashidhara Prasad
    • 1
  1. 1.Department of Studies in PhysicsUniversity of MysoreMysoreIndia
  2. 2.Department of ChemistrySaurashtra UniversityRajkotIndia

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