Development of a DNA sensor using a molecular logic gate
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- Bhattacharjee, D., Dey, D., Chakraborty, S. et al. J Biol Phys (2013) 39: 387. doi:10.1007/s10867-012-9295-3
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This communication reports the increase in fluorescence resonance energy transfer (FRET) efficiency between two laser dyes in the presence of deoxyribonucleic acid (DNA). Two types of molecular logic gates have been designed where DNA acts as input signal and fluorescence intensity of different bands are taken as output signal. Use of these logic gates as a DNA sensor has been demonstrated.