Journal of Biological Physics

, Volume 32, Issue 2, pp 177–181 | Cite as

Shapes of Mixed Phospholipid Vesicles

  • Gerardo Paredes-Quijada
  • Helim Aranda-Espinoza
  • Amir Maldonado
Short Note

Abstract

We studied the shape of phospholipid vesicles prepared by hydration of a mixture of phosphatidylcholine (SOPC) and phosphatidylserine (SOPS) in different proportions. The aim of the work is to obtain some insight into the influence of the chemical composition of a biomembrane on its shape. The optical microscopy results show that the shape of the vesicles depend on the SOPC:SOPS composition. For low SOPS contents, coiled cylindrical vesicles are observed. The results suggest that specific compositions of the SOPC:SOPS vesicles produce some spontaneous curvature on the membrane and then a coiling instability.

Keywords

biological membranes vesicles phospholipids vesicle coiling 

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References

  1. 1.
    Svetina, S. and Žekš, B.: Shape Behavior of Lipid Vesicles as the Basis of Some Cellular Processes. Anat. Rec. 268 (2002), 215–225.CrossRefGoogle Scholar
  2. 2.
    Huang, J., Swanson, J. E., Dibble, A. R. G., Hinderliter, A. K. and Feigenson, G. W.: Nonideal Mixing of Phosphatidylserine and Phosphatidylcholine in the Fluid Lamellar Phase. Biophys. J. 64 (1993), 413–425.CrossRefGoogle Scholar
  3. 3.
    Israelachvilli, J., Intermolecular and Surface Forces, Academic Press, 2nd edition, NY, 1992.Google Scholar
  4. 4.
    Lin, K.-C., Weiss, R. W. and McConnell, H. M.: Induction of Helical Liposomes by Ca2+-Mediated Intermembrane Binding. Nature 296 (1982), 164–165.CrossRefADSGoogle Scholar
  5. 5.
    Frette, V., Tsafrir, I., Guedeau-Boudeville, M.-A., Jullien, L., Kandel, D. and Stavans, J.: Coiling of Cylindrical Membrane Stacks with Anchored Polymers. Phys. Rev. Lett. 83 (1999), 2465–2468.CrossRefADSGoogle Scholar
  6. 6.
    Tsafrir, I., Guedeau-Boudeville, M. A., Kandel, D. and Stavans, J.: Coiling Instability of Multilamellar Membrane Tubes with Anchored Polymers. Phys. Rev. E 63 (2001), DOI: 10.1103/PhysRevE.63.031603.Google Scholar
  7. 7.
    Buchanan, M., Egelhaaf, S. U. and Cates, M. E.: Dynamics of Interface Instabilities in Nonionic Lamellar Phases. Langmuir 16(8) (2000), 3718–3726.CrossRefGoogle Scholar
  8. 8.
    Huang, J.-R., Zou, L.-N. and Witten, T. A.: Confined Multilamellae Prefer Cylindrical Morphology. A Theory of Myelin Formation. Eur. Phys. J. E Soft Matter 18(3) (2005), 279–285.CrossRefGoogle Scholar
  9. 9.
    Santangelo, C. D. and Pincus, P.: Coiling Instabilities of Multilamellar Tubes, Phys. Rev. E 66 (2002), DOI: 10.1103/PhysRevE.66.061501.Google Scholar
  10. 10.
    Nguyen, T. T., Gopal, A., Lee, K. Y. C. and Witten, T. A.: Surface Charge Relaxation and the Pearling Instability of Charged Surfactant Tubes. Phys. Rev. E 72 (2005), DOI: 10.1103/PhysRevE.72.051930.Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Gerardo Paredes-Quijada
    • 1
  • Helim Aranda-Espinoza
    • 2
  • Amir Maldonado
    • 3
  1. 1.Posgrado en Polímeros y MaterialesUniversidad de SonoraHermosilloMexico
  2. 2.Department of Chemical and Biomolecular Engineering and Bioengineering Graduate ProgramUniversity of MarylandCollege ParkUSA
  3. 3.Departamento de FísicaUniversidad de SonoraHermosilloMexico

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