Journal of Behavioral Medicine

, Volume 33, Issue 3, pp 209–218 | Cite as

The influence of quality of life and depressed mood on smoking cessation among medically ill smokers

  • Rashelle B. HayesEmail author
  • Shira Dunsiger
  • Belinda Borrelli


Disease diagnosis and poor quality of life has been suggested as a “teachable moment” that facilitates smoking cessation, yet many patients continue to smoke. One reason for this inconsistency may be the potential moderating role of depressed mood. This study prospectively examined the role of depressed mood on the relationship between physical quality of life (PQoL) and smoking cessation among medically ill smokers. We hypothesized that poorer PQoL will be associated with smoking cessation, but only among those with little to no depressed mood. Nurses delivered smoking cessation counseling to medically ill patients (N = 273) who continued to smoke despite past hospitalization. Participants were assessed at baseline and at 2, 6, and 12-months later. The interaction between PQoL and depressed mood significantly predicted 1) 7-day point prevalence abstinence rates at both 2 and 12 months post-treatment [2 months: adjusted OR = 1.005, 95%CI 1.001–1.009, p < .05; 12 months: adjusted OR = 1.007, 95%CI 1.002–1.011, p < .005)] and 2) continuous abstinence rates at both 2 and 12 months post-treatment [2 months: adjusted OR = 1.011, 95%CI 1.004–1.019, p < .005; 12 months: adjusted OR = 1.006, 95%CI 1.001–1.011, p < .05] even after controlling for important covariates. The odds of quitting smoking increased for every one-unit decrease in PQoL, but only among those with little to no depressed mood. Medically ill smokers with poor quality of life may need more intensive smoking cessation interventions that include mood management to help them quit smoking.


Depressed mood Smoking cessation Quality of life Chronic illness Medically ill smokers 



This research was supported by NCI grant R01 CA 7455301 to B. Borrelli.

Conflict of interest statement

The authors declare that there are no conflicts of interest and if requested, the journal can review data as appropriate.


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Rashelle B. Hayes
    • 1
    Email author
  • Shira Dunsiger
    • 2
  • Belinda Borrelli
    • 2
  1. 1.Division of Preventive and Behavioral MedicineUniversity of Massachusetts Medical SchoolWorcesterUSA
  2. 2.Centers for Behavioral and Preventive MedicineThe Warren Albert Brown Medical School & The Miriam HospitalProvidenceUSA

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