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The Sweet Taste Test: Relationships with Anhedonia Subtypes, Personality Traits, and Menstrual Cycle Phases

  • Jeffrey S. BedwellEmail author
  • Christopher C. Spencer
  • Cristina A. Chirino
  • John P. O’Donnell
Article

Abstract

A better understanding of the etiology and pathology related to distinct subtypes of anhedonia can lead to more efficacious personalized treatments. The current study advances knowledge on consummatory anhedonia - represented in the Research Domain Criteria (RDoC) subconstruct of Initial Response to Reward (IRR). The Sweet Taste Test (STT) has promise as a behavioral paradigm for IRR, as it is sensitive to manipulation of μ-opioid receptors. However, there is a lack of existing knowledge of how the STT relates to subtypes of anhedonia, personality traits, and phases of the menstrual cycle. To address these questions, we administered the STT to 72 nonpsychiatric adults (76% women; mean age: 19.11). As predicted, the hedonic slope reflecting increasing “like” ratings over increasing concentrations of five sucrose solutions (ranging from 0.05 M to 0.86 M), was lower in individuals reporting higher consummatory anhedonia (measured with Temporal Experience of Pleasure Scales - Consummatory Subscale) and in women in the mid-to-late luteal menstrual phase (days 20 to 28). Both effects were driven by lower hedonic ratings to the sweetest concentration. The hedonic slope was larger in individuals scoring higher on the Flight-Freeze-Avoidance System personality factor from the Reinforcement Sensitivity Theory Personality Questionnaire - driven by lower hedonic ratings for the least sweet concentration. No factor or aspect from the Big Five Aspects Scale related to hedonic ratings on the STT. The STT may be a valid and specific standardized behavioral paradigm to add to IRR, particularly if validated in a large transdiagnostic psychiatric sample.

Keywords

Sucrose Reward Consummatory anhedonia Initial responsiveness to reward attainment Research domain criteria Consummatory pleasure 

Notes

Acknowledgments

The authors would like to thank the following research assistants for their help on this project: Ashley Lee Lum, Pamela Askins, Doniya Milani, Jasmine Montero, Nicholas Picanso, and Brooke Fenton.

Compliance with Ethical Standards

Conflict of Interest

Jeffrey S. Bedwell, Christopher C. Spencer, Cristina A. Chirino, and John P. O’Donnell report no conflicts of interest related to this manuscript and study.

Experiment Participants

Research followed ethical principles described in the Declaration of Helsinki.

Ethical Approval

This study was approved by the Institutional Review Board of the University of Central Florida (IRB #: SBE-16-12,678).

Informed Consent

All participicipants provided informed consent for both the online and laboratory portions of this study.

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Authors and Affiliations

  1. 1.Department of PsychologyUniversity of Central FloridaOrlandoUSA

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