Journal of Biomolecular NMR

, Volume 55, Issue 2, pp 219–223 | Cite as

Solution structure of the Magnaporthe oryzae avirulence protein AvrPiz-t

  • Zhi-Min Zhang
  • Xu Zhang
  • Zi-Ren Zhou
  • Hong-Yu Hu
  • Maili Liu
  • Bo ZhouEmail author
  • Jiahai ZhouEmail author
NMR structure note

Biological context

Plants have evolved two major layers of defense mechanisms against invasion by diverse pathogens. When host membranes are exposed to pathogens, plants use extracellular surface receptors to identify pathogen-associated molecular patterns (PAMPs) and initiate so-called PAMP-triggered immunity (PTI) (Chisholm et al. 2006). Once pathogens gain hold in plants by suppressing this primary defense, plants express cytoplasmic resistance proteins that recognize pathogen-derived effector proteins and mount a more specialized defense mechanism referred to as effector-triggered immunity (ETI, Chisholm et al. 2006). To enable parasitism, pathogens usually use an arsenal of effector proteins that are delivered into plant cells to exert their primary function of interfering with the host immunity (Abramovitch et al. 2006; Feng et al. 2012; Wilton et al. 2010). However, effector proteins in some cases act as traitors by inducing effector-triggered immunity; these proteins are often...


Rice Blast Distance Restraint Chemical Shift Assignment Stable Fragment Side Chain Resonance Assignment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



This work was supported by grants from the National Program on Key Basic Research of China (2009CB918600, to J. Z. and M. L.), the National Grand Project for Medicine Innovation (2011ZX09506-001) and the Natural Science Foundation in China (30971878, to B. Z.). We are grateful to Prof. Chunyang Cao and Yan Zhang for valuable suggestions in NMR structure determination. We also thank Dr. Wenyu Wen for her help on H/D exchange experiments.

Supplementary material

10858_2012_9695_MOESM1_ESM.docx (95 kb)
Supplementary material 1 (DOCX 95 kb)


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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  1. 1.State Key Laboratory of Bio-organic and Natural Products ChemistryShanghai Institute of Organic Chemistry, Chinese Academy of SciencesShanghaiChina
  2. 2.Wuhan Center for Magnetic Resonance, State Key Laboratory of Magnetic Resonance and Atomic and Molecular PhysicsWuhan Institute of Physics and Mathematics, Chinese Academy of SciencesWuhanChina
  3. 3.State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell BiologyShanghai Institutes for Biological Sciences, Chinese Academy of SciencesShanghaiChina
  4. 4.State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease ControlInstitute of Virology and Biotechnology, Zhejiang Academy of Agricultural SciencesHangzhouChina

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