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Electrospun polyvinyl alcohol membranes incorporated with green synthesized silver nanoparticles for wound dressing applications

  • Robin Augustine
  • Anwarul Hasan
  • V. K Yadu Nath
  • Jince Thomas
  • Anitha Augustine
  • Nandakumar Kalarikkal
  • Ala-Eddin Al Moustafa
  • Sabu Thomas
Biomaterials Synthesis and Characterization Original Research
  • 75 Downloads
Part of the following topical collections:
  1. Biomaterials Synthesis and Characterization

Abstract

Electrospun membranes have the potential to act as an effective barrier for wounds from the external environment to prevent pathogens. In addition, materials with good antibacterial properties can effectively fight off the invading pathogens. In this paper, we report the development of a novel electrospun polyvinyl alcohol (PVA) membrane containing biosynthesized silver nanoparticle (bAg) for wound dressing applications. Plant extract from a medicinal plant Mimosa pudica was utilized for the synthesis of bAg. Synthesized bAg were characterized by Ultraviolet-Visible (UV) Spectroscopy and Fourier Transform Infrared Spectroscopy (FTIR). The morphology of bAg was obtained from Transmission Electron Microscopy (TEM) and found that they were spherical in morphology with average particle size 7.63 ± 1.2 nm. bAg nanoparticles incorporated PVA membranes were characterized using several physicochemical techniques such as Scanning Electron Microscopy (SEM), Energy Dispersive X-Ray Spectroscopy (EDS) and X-Ray Diffraction (XRD) analysis. Experimental results confirmed the successful incorporation of bAg in PVA fibers. PVA nanofiber membranes incorporated with bAg showed good mechanical strength, excellent exudate uptake capacity, antibacterial activity, blood compatibility and cytocompatibility.

Notes

Funding

This article was made possible by the NPRP9-144-3-021 grant funded by Qatar national Research Fund (a part of Qatar Foundation). The statements made here are totally responsibility of authors.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Mechanical and Industrial Engineering, College of EngineeringQatar UniversityDohaQatar
  2. 2.Biomedical Research CentreQatar UniversityDohaQatar
  3. 3.International and Inter University Centre for Nanoscience and NanotechnologyMahatma Gandhi UniversityKottayamIndia
  4. 4.Department of ChemistryBishop Kurialacherry College for WomenKottayamIndia
  5. 5.School of Pure and Applied PhysicsMahatma Gandhi UniversityKottayamIndia
  6. 6.College of MedicineQatar UniversityDohaQatar
  7. 7.School of Chemical SciencesMahatma Gandhi UniversityKottayamIndia

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