Comparison of osteoconductivity and absorbability of beta-tricalcium phosphate and hydroxyapatite in clinical scenario of opening wedge high tibial osteotomy

  • Kwang-Jun OhEmail author
  • Young-Bong Ko
  • Sagar Jaiswal
  • In-Cheul Whang
Clinical Applications of Biomaterials Original Research
Part of the following topical collections:
  1. Clinical Applications of Biomaterials


The purpose of this study was to compare the osteoconductivity, and absorbability of hydroxyapatite or beta-tricalcium phosphate in clinical scenario of opening wedge high tibial osteotomy Total 41 knees of 40 patients with follow up period of more than 1 year were enrolled. These patients were divided into two groups, Group I (22 knees, 21 patients) used hydroxyapatite and Group II (19 knees, 19 patients) used beta-tricalcium phosphate as a substitute in the opening gap. According to proven method, the osteoconductivity was assessed radiographically by the extent of new bone formation at osteotomy space and absorbability was evaluated by measuring the area occupied by substitute at immediate postoperative, postoperative 6 months and 1 year. Regarding preoperative demographic data, no significant differences were found between two groups. No statistically significant differences were found between two groups regarding lower limb alignment (mechanical femorotibial angle, weight-bearing line%) and posterior tibial slope at postoperative and final follow up radiographs. Concerning the osteoconductivity, there were no significant differences between two groups in any zone. However, the absorption rate was significantly greater in the Group II than in Group I at 6 months (Group I: 13.7 ± 6.8, group II: 35.3 ± 15.8, P = 0.001) and 1 year (Group I: 24.2 ± 6.3, Group II: 49.6 ± 14.3, P < 0.0001). The complications related to bone substitutes were not observed. Both hydroxyapatite and beta-tricalcium phosphate showed satisfactory gap healing without complications and can be successfully used as alternative healing materials in opening wedge high tibial osteotomy. Our study showed that beta-tricalcium phosphate has superior absorbability than hydroxyapatite. But osteoconductivity showed no significant difference.


High Tibial Osteotomy Bone Substitute Posterior Tibial Slope Open Wedge High Tibial Osteotomy Picture Archive Communication System 
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This paper was supported by Konkuk University.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing interests.


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Kwang-Jun Oh
    • 1
    Email author
  • Young-Bong Ko
    • 1
  • Sagar Jaiswal
    • 1
  • In-Cheul Whang
    • 2
  1. 1.Konkuk University Medical Center, Konkuk University School of MedicineSeoulRepublic of Korea
  2. 2.Whangincheul Orthopaedic Clinic SurgeryGyeonggi ProvinceRepublic of Korea

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