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A bioresorbable polylactide implant used in bone cyst filling

  • Krzysztof FicekEmail author
  • Jolanta Filipek
  • Piotr Wojciechowski
  • Konrad Kopec
  • Stodolak-Zych Ewa
  • Stanislaw Blazewicz
Biomaterials Synthesis and Characterization Clinical Investigation
Part of the following topical collections:
  1. Biomaterials Synthesis and Characterization

Abstract

The aims in treating patients diagnosed with critical-sized bone defects resulting from bone cysts are to replace the lost bone mass after its removal and to restore function. The standard treatment is autologous or allogeneic bone transplantation, notwithstanding the known consequences and risks due to possible bone infection, donor site morbidity, bleeding and nerve injury and possible undesirable immune reactions. Additionally, allogeneic grafts are inhomogeneous, with a mosaic of components with difficult-to-predict regenerative potential, because they consist of cancellous bone obtained from different bones from various cadavers. In the present study, a 22-year-old patient with a history of right humerus fracture due to bone cysts was diagnosed with recurrent cystic lesions based on X-ray results. The patient qualified for an experimental program, in which he was treated with the application of a bioresorbable polylactide hybrid sponge filled with autologous platelet-rich plasma. Computed tomography and magnetic resonance imaging performed 3, 6, and 36 months after surgery showed progressive ossification and bone formation inside the defect cavity in the humerus. Three years after treatment with the bone substitute, the patient is pain free, and the cystic lesions have not reoccurred.

Keywords

Sponge Bone Defect Cystic Lesion Bone Cyst Bone Substitute 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

This study was supported by the kind cooperation of Bioimplant, Ltd., Poland.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Krzysztof Ficek
    • 1
    • 2
    • 3
    Email author
  • Jolanta Filipek
    • 1
  • Piotr Wojciechowski
    • 1
    • 4
  • Konrad Kopec
    • 1
    • 4
  • Stodolak-Zych Ewa
    • 5
  • Stanislaw Blazewicz
    • 5
  1. 1.Galen-OrthopaedicsBierunPoland
  2. 2.Department of Physical Culture and Health PromotionUniversity of SzczecinSzczecinPoland
  3. 3.Academy of Physical EducationKatowicePoland
  4. 4.Department of Orthopaedics and TraumatologyMedical University of Silesia, School of Medicine in KatowiceKatowicePoland
  5. 5.Department of Biomaterials, Faculty of Materials Science and CeramicsAGH University of Science and TechnologyKrakowPoland

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