45S5 Bioglass®–MWCNT composite: processing and bioactivity

  • Harshit Porwal
  • Mehdi EstiliEmail author
  • Alina Grünewald
  • Salvatore Grasso
  • Rainer Detsch
  • Chunfeng Hu
  • Yoshio Sakka
  • Aldo R. BoccacciniEmail author
  • Mike J. ReeceEmail author
Biomaterials Synthesis and Characterization
Part of the following topical collections:
  1. Biomaterials Synthesis and Characterization


Multi-walled carbon nanotube (MWCNT)–Bioglass (BG) matrix composite was fabricated using a facile and scalable aqueous colloidal processing method without using any surfactants followed by spark plasma sintering (SPS) consolidation. The individual MWCNTs were initially uniformly dispersed in water and then entirely immobilized on the BG particles during the colloidal processing, avoiding their common re-agglomeration during the water-removal and drying step, which guaranteed their uniform dispersion within the dense BG matrix after the consolidation process. SPS was used as a fast sintering technique to minimise any damage to the MWCNT structure during the high-temperature consolidation process. The electrical conductivity of BG increased by 8 orders of magnitude with the addition of 6.35 wt% of MWCNTs compared to pure BG. Short-duration tests were used in the present study as a preliminary evaluation to understand the effect of incorporating MWCNTs on osteoblast-like cells. The analysed cell proliferation, viability and phenotype expression of MG-63 cells showed inhibition on 45S5 Bioglass®–MWCNT composite surfaces.


Spark Plasma Sinter Pristine MWCNTs Bone Scaffold Colloidal Processing MWCNT Composite 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The authors would like to thank European Union’s Seventh Framework Program managed by REA-Research Executive Agency (Marie Curie Action, GlaCERCo GA 264526) and International Center for Young Scientists (ICYS) of National Institute for Materials Science (NIMS), Tsukuba, Japan for their support and funding for this research. Prof. M.J. Reece would like to acknowledge the support of Sunchon National University, South Korea, through the BK21 + programme.


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Harshit Porwal
    • 1
    • 2
  • Mehdi Estili
    • 3
    Email author
  • Alina Grünewald
    • 4
  • Salvatore Grasso
    • 1
    • 2
  • Rainer Detsch
    • 4
  • Chunfeng Hu
    • 5
  • Yoshio Sakka
    • 5
  • Aldo R. Boccaccini
    • 4
    Email author
  • Mike J. Reece
    • 1
    • 2
    Email author
  1. 1.School of Engineering and Material ScienceQueen Mary University of LondonLondonUK
  2. 2.Nanoforce Technology LimitedLondonUK
  3. 3.International Center for Young Scientists (ICYS)National Institute for Materials Science (NIMS)TsukubaJapan
  4. 4.Department of Materials Science and Engineering, Institute of BiomaterialsUniversity of Erlangen-NurembergErlangenGermany
  5. 5.Materials Processing UnitNational Institute for Materials Science (NIMS)TsukubaJapan

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