Electrophoretic deposition of mesoporous bioactive glass on glass–ceramic foam scaffolds for bone tissue engineering

  • Sonia Fiorilli
  • Francesco Baino
  • Valentina Cauda
  • Marco Crepaldi
  • Chiara Vitale-Brovarone
  • Danilo Demarchi
  • Barbara Onida
Engineering and Nano-engineering Approaches for Medical Devices
Part of the following topical collections:
  1. Engineering and Nano-engineering Approaches for Medical Devices


In this work, the coating of 3-D foam-like glass–ceramic scaffolds with a bioactive mesoporous glass (MBG) was investigated. The starting scaffolds, based on a non-commercial silicate glass, were fabricated by the polymer sponge replica technique followed by sintering; then, electrophoretic deposition (EPD) was applied to deposit a MBG layer on the scaffold struts. EPD was also compared with other techniques (dipping and direct in situ gelation) and it was shown to lead to the most promising results. The scaffold pore structure was maintained after the MBG coating by EPD, as assessed by SEM and micro-CT. In vitro bioactivity of the scaffolds was assessed by immersion in simulated body fluid and subsequent evaluation of hydroxyapatite (HA) formation. The deposition of a MBG coating can be a smart strategy to impart bioactive properties to the scaffold, allowing the formation of nano-structured HA agglomerates within 48 h from immersion, which does not occur on uncoated scaffold surfaces. The mechanical properties of the scaffold do not vary after the EPD (compressive strength ~19 MPa, fracture energy ~1.2 × 106 J m−3) and suggest the suitability of the prepared highly bioactive constructs as bone tissue engineering implants for load-bearing applications.


Simulated Body Fluid Bioactive Glass Wollastonite Bone Tissue Engineering Electrophoretic Deposition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Supplementary material

10856_2014_5346_MOESM1_ESM.pdf (85 kb)
Supplementary material 1 (PDF 85 kb)


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Sonia Fiorilli
    • 1
  • Francesco Baino
    • 1
  • Valentina Cauda
    • 2
  • Marco Crepaldi
    • 2
  • Chiara Vitale-Brovarone
    • 1
    • 3
  • Danilo Demarchi
    • 4
  • Barbara Onida
    • 1
  1. 1.Dipartimento di Scienza Applicata e TecnologiaPolitecnico di TorinoTurinItaly
  2. 2.Center for Space Human Robotics@PoliToIstituto Italiano di TecnologiaTurinItaly
  3. 3.Bionica Tech S.r.lTurinItaly
  4. 4.Dipartimento di Elettronica e TelecomunicazioniPolitecnico di TorinoTurinItaly

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