Decreasing the diabetic complication by vanadyl(VO)2+/vitamin B6 complex in alloxan-induced diabetic mice
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- El-Shenawy, N.S., Refat, M.S. & Fakihi, F.H. J Mater Sci: Mater Med (2013) 24: 911. doi:10.1007/s10856-013-4852-2
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The scope of this work was to synthesize a novel bifunctionalized vanadyl(VO)2+/vitamin B6 complex. The diabetic therapeutic efficacy of the new complex was investigated in alloxan-induced diabetic mice. The results suggested that vanadyl(VO)2+/vit B6 complex has an anti-diabetic potency, improved the lipid profile and liver and kidney functions. The new complex possesses an antioxidant activity. The current results support the therapeutic potentiality of vanadyl(VO)2+/vitamin B6 complex for the management of diabetes.