Decreasing the diabetic complication by vanadyl(VO)2+/vitamin B6 complex in alloxan-induced diabetic mice


DOI: 10.1007/s10856-013-4852-2

Cite this article as:
El-Shenawy, N.S., Refat, M.S. & Fakihi, F.H. J Mater Sci: Mater Med (2013) 24: 911. doi:10.1007/s10856-013-4852-2


The scope of this work was to synthesize a novel bifunctionalized vanadyl(VO)2+/vitamin B6 complex. The diabetic therapeutic efficacy of the new complex was investigated in alloxan-induced diabetic mice. The results suggested that vanadyl(VO)2+/vit B6 complex has an anti-diabetic potency, improved the lipid profile and liver and kidney functions. The new complex possesses an antioxidant activity. The current results support the therapeutic potentiality of vanadyl(VO)2+/vitamin B6 complex for the management of diabetes.

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Biology Department, Faculty of ScienceTaif UniversityTaifSaudi Arabia
  2. 2.Zoology Department, Faculty of ScienceSuez Canal UniversityIsmailiaEgypt
  3. 3.Department of Chemistry, Faculty of SciencePort Said UniversityPort SaidEgypt
  4. 4.Department of Chemistry, Faculty of ScienceTaif UniversityTaifSaudi Arabia

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