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Bioactive glass-derived trabecular coating: a smart solution for enhancing osteointegration of prosthetic elements

  • Chiara Vitale-Brovarone
  • Francesco Baino
  • Francesca Tallia
  • Cristina Gervasio
  • Enrica Verné
Article

Abstract

In this work, the use of foam-like glass–ceramic scaffolds as trabecular coatings on ceramic prosthetic devices to enhance implant osteointegration is proposed. The feasibility of this innovative device was explored in a simplified, flat geometry: glass–ceramic scaffolds, prepared by polymeric sponge replication and mimicking the trabecular architecture of cancellous bone, were joined to alumina square substrates by a dense glass coating (interlayer). The role played by different formulations of starting glasses was examined, with particular care to the effect on the mechanical properties and bioactivity of the final coating. Microindentations at the coating/substrate interface and tensile tests were performed to evaluate the bonding strength between the sample’s components. In vitro bioactive behaviour was assessed by soaking in simulated body fluid and evaluating the apatite formation on the surface and inside the pores of the trabecular coating. The concepts disclosed in the present study can have a significant impact in the field of implantable devices, suggesting a valuable alternative to traditional, often invasive bone-prosthesis fixation.

Keywords

Simulated Body Fluid Bioactive Glass Wollastonite Alumina Substrate Glass Powder 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

This work was partly funded by the EU Network of Excellence project “Knowledge-based Multicomponent Materials for Durable and Safe Performance” (KMM-NoE, NMP3-CT-2004-502243). Prof. Milena Salvo is gratefully acknowledged for fruitful discussions.

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Chiara Vitale-Brovarone
    • 1
  • Francesco Baino
    • 1
  • Francesca Tallia
    • 1
  • Cristina Gervasio
    • 1
  • Enrica Verné
    • 1
  1. 1.Institute of Materials Engineering and Physics, Applied Science and Technology DepartmentPolitecnico di TorinoTurinItaly

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