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A novel antibacterial resin composite for improved dental restoratives

  • Yiming Weng
  • Leah Howard
  • Xia Guo
  • Voon Joe Chong
  • Richard L. Gregory
  • Dong XieEmail author
Article

Abstract

A novel furanone-containing antibacterial resin composite has been prepared and evaluated. compressive strength (CS) and Streptococcus mutans viability were used to evaluate the mechanical strength and antibacterial activity of the composites. The modified resin composites showed a significant antibacterial activity without substantially decreasing the mechanical strengths. With 5–30 % addition of the furanone derivative, the composite kept its original CS unchanged but showed a significant antibacterial activity with a 16–68 % reduction in the S. mutans viability. Further, the antibacterial function of the new composite was not affected by human saliva. The aging study indicates that the composite may have a long-lasting antibacterial function. Within the limitations of this study, it appears that the experimental antibacterial resin composite may potentially be developed into a clinically attractive dental restorative due to its high mechanical strength and antibacterial function.

Keywords

Compressive Strength Flexural Strength Resin Composite Quaternary Ammonium Salt DMAEMA 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

This work was sponsored by NIH challenge grant (RC1) DE020614.

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Yiming Weng
    • 1
  • Leah Howard
    • 1
  • Xia Guo
    • 1
  • Voon Joe Chong
    • 1
  • Richard L. Gregory
    • 2
  • Dong Xie
    • 1
    Email author
  1. 1.Department of Biomedical Engineering, Purdue School of Engineering and TechnologyIndiana University–Purdue University at IndianapolisIndianapolisUSA
  2. 2.Department of Oral Biology, School of DentistryIndiana UniversityIndianapolisUSA

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