Properties of xyloglucan hydrogel as the biomedical sustained-release carriers

  • Didi Chen
  • Pei Guo
  • Sha Chen
  • Yu Cao
  • Wanzhen Ji
  • Xia Lei
  • Lina Liu
  • Peiguang Zhao
  • Ruihong Wang
  • Chao Qi
  • Yanli Liu
  • Hongxuan He
Article

DOI: 10.1007/s10856-012-4564-z

Cite this article as:
Chen, D., Guo, P., Chen, S. et al. J Mater Sci: Mater Med (2012) 23: 955. doi:10.1007/s10856-012-4564-z

Abstract

This study introduces an easy method of preparing xyloglucan hydrogel from xyloglucan, which is purified from tamarind seed gum. Xyloglucan hydrogel was prepared in 2 wt% solution by treating with β-galactosidase. Physical and chemical properties (molecular mass, size and viscosity) of xyloglucan hydrogel and xyloglucan solution were tested for a comparison. Experiments of drug release in vitro and in vivo were operated to investigate the potentialities of xyloglucan hydrogel as the biomedical sustained-release carriers for drug delivery system.

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Didi Chen
    • 1
  • Pei Guo
    • 1
  • Sha Chen
    • 1
  • Yu Cao
    • 1
    • 2
  • Wanzhen Ji
    • 1
  • Xia Lei
    • 1
  • Lina Liu
    • 1
  • Peiguang Zhao
    • 1
  • Ruihong Wang
    • 1
  • Chao Qi
    • 2
  • Yanli Liu
    • 2
  • Hongxuan He
    • 3
  1. 1.Key Laboratory of Pesticide and Chemical Biology (Ministry of Education), College of ChemistryCentral China Normal UniversityWuhanPeople’s Republic of China
  2. 2.Hubei Key Laboratory of Genetic Regulation and Integrative Biology, College of Life ScienceCentral China Normal UniversityWuhanPeople’s Republic of China
  3. 3.National Research Center for Wildlife Born Diseases, Key Laboratory of Animal Ecology and Conservation Biology, Institute of ZoologyChinese Academy of SciencesBeijingChina

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