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Bioactive glass granules: a suitable bone substitute material in the operative treatment of depressed lateral tibial plateau fractures: a prospective, randomized 1 year follow-up study

  • Jouni T. Heikkilä
  • Juha Kukkonen
  • Allan J. Aho
  • Susanna Moisander
  • Timo Kyyrönen
  • Kimmo Mattila
Article

Abstract

Purpose of this study was to compare bioactive glass and autogenous bone as a bone substitute material in tibial plateau fractures. We designed a prospective, randomized study consisting of 25 consecutive operatively treated patients with depressed unilateral tibial comminuted plateau fracture (AO classification 41 B2 and B3).14 patients (7 females, 7 males, mean age 57 years, range 25–82) were randomized in the bioglass group (BG) and 11 patients (6 females, 5 males, mean age 50 years, range 31–82) served as autogenous bone control group (AB). Clinical examination of the patients was performed at 3 and 12 months, patients’ subjective and functional results were evaluated at 12 months. Radiological analysis was performed preoperatively, immediately postoperatively and at 3 and 12 months. The postoperative redepression for both studied groups was 1 mm until 3 months and remained unchanged at 12 months. No differences were identified in the subjective evaluation, functional tests and clinical examination between the two groups during 1 year follow-up. We conclude that bioactive glass granules can be clinically used as filler material instead of autogenous bone in the lateral tibial plateau compression fractures.

Keywords

Iliac Crest Bioactive Glass Plain Film Calcium Phosphate Cement Hydroxylapatite 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

Sincere thanks to Biostatistician Hans Helenius, MSc., Head of the Department of Biostatistics, University of Turku, for his valuable help in organizing the statistical analysis of the data.

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Jouni T. Heikkilä
    • 1
  • Juha Kukkonen
    • 2
  • Allan J. Aho
    • 2
  • Susanna Moisander
    • 2
  • Timo Kyyrönen
    • 3
    • 4
  • Kimmo Mattila
    • 4
    • 5
  1. 1.Sports Clinic MehiläinenTurkuFinland
  2. 2.Department of TraumatologyTurku University HospitalTurkuFinland
  3. 3.Medical Imaging Centre of Southwest Finland, Salo District HospitalUniversity of TurkuTurkuFinland
  4. 4.Department of Diagnostic RadiologyUniversity of TurkuTurkuFinland
  5. 5.Medical Imaging Centre of Southwest FinlandTurku University HospitalTurkuFinland

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