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Antibacterial effect of bioactive glasses on clinically important anaerobic bacteria in vitro

  • Outi LeppärantaEmail author
  • Minna Vaahtio
  • Timo Peltola
  • Di Zhang
  • Leena Hupa
  • Mikko Hupa
  • Heimo Ylänen
  • Jukka I. Salonen
  • Matti K. Viljanen
  • Erkki Eerola
Article

Abstract

Bioactive glasses (BAGs) of different compositions have been studied for decades for clinical use and they have found many dental and orthopaedic applications. Particulate BAGs have also been shown to have antibacterial properties. This large-scale study shows that two bioactive glass powders (S53P4 and 13–93) and a sol–gel derived material (CaPSiO II) have an antibacterial effect on 17 clinically important anaerobic bacterial species. All the materials tested demonstrated growth inhibition, although the concentration and time needed for the effect varied depending on the BAG. Glass S53P4 had a strong growth-inhibitory effect on all pathogens tested. Glass 13–93 and sol–gel derived material CaPSiO II showed moderate antibacterial properties.

Keywords

Antibacterial Effect Bioactive Glass Glass Network Live Bacterium Bacteriostatic Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgement

This study was supported by the Finnish Funding Agency for Technology and Innovation (TEKES).

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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Outi Leppäranta
    • 1
    • 2
    Email author
  • Minna Vaahtio
    • 3
    • 4
  • Timo Peltola
    • 3
    • 4
  • Di Zhang
    • 5
  • Leena Hupa
    • 5
  • Mikko Hupa
    • 5
  • Heimo Ylänen
    • 3
    • 5
  • Jukka I. Salonen
    • 3
  • Matti K. Viljanen
    • 1
  • Erkki Eerola
    • 1
  1. 1.Department of Medical MicrobiologyUniversity of TurkuTurkuFinland
  2. 2.Finnish Food Safety Authority EviraHelsinkiFinland
  3. 3.Turku Biomaterials CentreUniversity of TurkuTurkuFinland
  4. 4.Vivoxid Ltd.TurkuFinland
  5. 5.Process Chemistry CentreÅbo Akademi UniversityTurkuFinland

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