Dependence of kinetic variables in the short-term release of Hg2+, Cu2+ and Zn2+ ions into synthetic saliva from an high-copper dental amalgam

  • Guglielmo Campus
  • Franklin Garcia-Godoy
  • Leonardo Gaspa
  • Angelo Panzanelli
  • Paola C. Piu
  • Giovanni Micera
  • Pierfranca Lugliè
  • Gavino Sanna


The short term (up to 14 days after restoration) release of selected ions (i.e., Hg2+, Cu2+ and Zn2+) from Dispersalloy® into artificial saliva has been evaluated in regards to the nature of the saliva (Fusayama and McCarty and Shklar’s solutions), the amount of amalgam, the time of contact and the periodical renewal (every 48 h interval) of artificial saliva. The evaluation of the ionic fraction of such metals has been accomplished by using anodic stripping methods (i.e., Differential Pulse Anodic Stripping Voltammetry, DPASV) with a 7 μm graphite disk microelectrode as a working electrode. Data obtained in this work are almost unprecedented in the literature due the fact that such analytical method exclude metals in non-ionic forms (e.g., metals or organometallic compounds). The high concentrations measured in every experimental condition confirm the concern for the short-term release of metals from amalgam into saliva.


Artificial Saliva KSCN Dental Amalgam Differential Pulse Anodic Strip Voltammetry Heavy Metal Trace 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Supplementary material

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ESM 1 (DOC 248 kb)


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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Guglielmo Campus
    • 1
    • 2
  • Franklin Garcia-Godoy
    • 3
  • Leonardo Gaspa
    • 2
    • 4
  • Angelo Panzanelli
    • 5
  • Paola C. Piu
    • 5
  • Giovanni Micera
    • 5
  • Pierfranca Lugliè
    • 1
  • Gavino Sanna
    • 2
    • 5
  1. 1.Dental InstituteUniversity of SassariSassariItaly
  2. 2.Nanoworld Institute, Nanoscience LaboratoriesUniversity of SassariSassariItaly
  3. 3.College of Dental MedicineNova Southeastern UniversityFort LauderdaleUSA
  4. 4.Biomedical Sciences DepartmentUniversity of SassariSassariItaly
  5. 5.Chemistry DepartmentUniversity of SassariSassariItaly

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