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Macroporous hydrogels based on 2-hydroxyethyl methacrylate

Part II Copolymers with positive and negative charges, polyelectrolyte complexes
  • M. PřádnýEmail author
  • P. Lesný
  • K. SmetanaJr.
  • J. Vacík
  • M. šlouf
  • J. Michálek
  • E. Syková
Article

Abstract

Crosslinked macroporous hydrogels based on 2-hydroxyethyl methacrylate (HEMA)—[2-(methacryloyloxy)ethyl]trimethylammonium chloride (MOETACl) copolymer, HEMA-MOETACl—methacrylic acid (MA) terpolymer, and on a polyelectrolyte complex of HEMA—MA copolymer with poly(MOETACl) were prepared. All the hydrogels were prepared in the presence of fractionated sodium chloride particles. The hydrogels were characterized by the number of pores and the total volume of all pores in unit volume, the average volume and the average diameter of single pore. Morphology of the hydrogels was investigated by confocal and scanning electron microscopy. The hydrogels based on polyelectrolyte complexes were also characterized by chemical composition. Homogeneous (non-porous) hydrogels with the same composition as macroporous hydrogels were prepared and characterized by their biocompatibility.

Keywords

Chloride Scanning Electron Microscopy Ethyl Sodium Chloride Methacrylate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science + Business Media, Inc. 2005

Authors and Affiliations

  • M. Přádný
    • 1
    • 2
    Email author
  • P. Lesný
    • 2
  • K. SmetanaJr.
    • 3
  • J. Vacík
    • 1
    • 2
  • M. šlouf
    • 1
    • 2
  • J. Michálek
    • 1
    • 2
  • E. Syková
    • 2
  1. 1.Institute of Macromolecular ChemistryAcademy of Sciences of the Czech RepublicPrague 6Czech Republic
  2. 2.Center for Cell Therapy and Tissue RepairCharles UniversityPrague 5Czech Republic
  3. 3.Institute of Anatomy, 1st Faculty of MedicineCharles UniversityPrague 2Czech Republic

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