Osteoblast cell adhesion on a laser modified zirconia based bioceramic


DOI: 10.1007/s10856-005-2608-3

Cite this article as:
Hao, L., Lawrence, J. & Chian, K.S. J Mater Sci: Mater Med (2005) 16: 719. doi:10.1007/s10856-005-2608-3


Due to their attractive mechanical properties, bioinert zirconia bioceramics are frequently used in the high load-bearing sites such as orthopaedic and dental implants, but they are chemically inert and do not naturally form a direct bond with bone and thus do not provide osseointegration. A CO2 laser was used to modify the surface properties with the aim to achieve osseointegration between bioinert zirconia and bone. The surface characterisation revealed that the surface roughness decreased and solidified microstructure occurred after laser treatment. Higher wettability characteristics generated by the CO2 laser treatment was primarily due to the enhancement of the surface energy, particularly the polar component, determined by microstructural changes. An in vitro test using human fetal osteoblast cells (hFOB) revealed that osteoblast cells adhere better on the laser treated sample than the untreated sample. The change in the wettability characteristics could be the main mechanism governing the osteoblast cell adhesion on the YPSZ.

Copyright information

© Springer Science + Business Media, Inc. 2005

Authors and Affiliations

  1. 1.Wolfson School of Mechanical and Manufacturing Engineering, Rapid Manufacturing Research GroupLoughborough UniversityUK
  2. 2.Manufacturing Engineering Division, School of Mechanical & Production EngineeringNanyang Technological University (NTU)Singapore

Personalised recommendations