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Journal of Materials Science

, Volume 54, Issue 5, pp 4409–4422 | Cite as

Corrosion behavior and cytocompatibility of nano-grained AZ31 Mg alloy

  • W. T. Huo
  • X. Lin
  • S. Yu
  • Z. T. Yu
  • W. Zhang
  • Y. S. Zhang
Metals
  • 37 Downloads

Abstract

The high corrosion rate of Mg alloys has hindered their wider use in orthopedic applications. In order to decrease the corrosion rate and to improve the bioactivity, a modified nanocrystalline (NC) surface layer with an average grain size of 70 nm and a thickness of 70 μm on the topmost surface of coarse-grained (CG) AZ31 alloy was successfully achieved by means of a surface nanocrystallization technique called sliding friction treatment (SFT). It showed that the extreme grain refinement in NC layer was favorably capable of enhancing the protective efficiency of the corrosion product layer and alleviating the susceptibility to localized corrosion. Moreover, SFT-induced second-phase particles fragmentation also helped to hinder micro-galvanic corrosion. Resultantly, the NC sample exhibited notably enhanced corrosion resistance as compared to the CG counterpart (e.g., the average hydrogen evolution rate of AZ31 during 170 h immersion in simulated body fluid (SBF) solution was reduced from 0.12 to 0.068 mL cm−2 h−1 after SFT processing). Meanwhile, the in vitro results confirmed that SFT processing enhanced the cytocompatibility of AZ31 Mg alloy to osteoblasts, which also benefited from the improved corrosion resistance induced by grain size reduction. Therefore, our study suggests a promising approach for the fabrication of biodegradable Mg alloy with modified properties.

Notes

Acknowledgements

This work was supported by National Natural Science Foundation of China (Grant Nos. 51701166, 51701163 and 81501858), State Key Laboratory for Advanced Metals and Materials of China (2017-Z01), CAS “Light of West China” Program (XAB2017AW12), Scientific Research Program in Weiyang District of Xi’an (201820) and Innovation team in key areas of Shaanxi Province (2016KCT-30).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

References

  1. 1.
    Sankara Narayanan TSN, Park IS, Lee MH (2014) Strategies to improve the corrosion resistance of microarc oxidation (MAO) coated magnesium alloys for degradable implants: prospects and challenges. Prog Mater Sci 60:1–71CrossRefGoogle Scholar
  2. 2.
    Silva CLP, Oliveira AC, Costa CGF, Figueiredo RB, de Fátima LM, Pereira MM, Lins VFC, Langdon TG (2017) Effect of severe plastic deformation on the biocompatibility and corrosion rate of pure magnesium. J Mater Sci 52:5992–6003.  https://doi.org/10.1007/s10853-017-0835-x CrossRefGoogle Scholar
  3. 3.
    Aung NN, Zhou W (2010) Effect of grain size and twins on corrosion behaviour of AZ31B magnesium alloy. Corros Sci 52:589–594CrossRefGoogle Scholar
  4. 4.
    Ding Y, Lin J, Wen C, Zhang D, Li Y (2016) Mechanical properties, in vitro corrosion and biocompatibility of newly developed biodegradable Mg–Zr–Sr–Ho alloys for biomedical applications. Sci Rep 6:31990CrossRefGoogle Scholar
  5. 5.
    Zhang CZ, Zhu SJ, Wang LG, Guo RM, Yue GC, Guan SK (2016) Microstructures and degradation mechanism in simulated body fluid of biomedical Mg–Zn–Ca alloy processed by high pressure torsion. Mater Des 96:54–62CrossRefGoogle Scholar
  6. 6.
    Zeng RC, Cui LY, Jiang K, Liu R, Zhao BD, Zheng YF (2016) In vitro corrosion and cytocompatibility of a microarc oxidation coating and poly(l-lactic acid) composite coating on Mg-1Li-1Ca alloy for orthopedic implants. ACS Appl Mater Interfaces 8:10014–10028CrossRefGoogle Scholar
  7. 7.
    Toorani M, Aliofkhazraei M, Golabadi M, Rouhaghdam AS (2017) Effect of lanthanum nitrate on the microstructure and electrochemical behavior of PEO coatings on AZ31 Mg alloy. J Alloys Compd 719:242–255CrossRefGoogle Scholar
  8. 8.
    Agarwal S, Curtin J, Duffy B, Jaiswal S (2016) Biodegradable magnesium alloys for orthopaedic applications: a review on corrosion, biocompatibility and surface modifications. Mater Sci Eng C 68:948–963CrossRefGoogle Scholar
  9. 9.
    Luo D, Liu Y, Yin X, Wang H, Han Z, Ren L (2018) Corrosion inhibition of hydrophobic coatings fabricated by micro-arc oxidation on an extruded Mg–5Sn–1Zn alloy substrate. J Alloys Compd 731:731–738CrossRefGoogle Scholar
  10. 10.
    Ding Y, Wen C, Hodgson P, Li Y (2014) Effects of alloying elements on the corrosion behavior and biocompatibility of biodegradable magnesium alloys: a review. J Mater Chem B 2:1912–1933CrossRefGoogle Scholar
  11. 11.
    Liu C, Fu X, Pan H, Wan P, Wang L, Tan L, Wang K, Zhao Y, Yang K, Chu PK (2016) Biodegradable Mg–Cu alloys with enhanced osteogenesis, angiogenesis, and long-lasting antibacterial effects. Sci Rep 6:27374CrossRefGoogle Scholar
  12. 12.
    Turan ME, Sun Y, Akgul Y, Turen Y, Ahlatci H (2017) The effect of GNPs on wear and corrosion behaviors of pure magnesium. J Alloys Compd 724:14–23CrossRefGoogle Scholar
  13. 13.
    Gao JH, Guan SK, Ren ZW, Sun YF, Zhu SJ, Wang B (2011) Homogeneous corrosion of high pressure torsion treated Mg–Zn–Ca alloy in simulated body fluid. Mater Lett 65:691–693CrossRefGoogle Scholar
  14. 14.
    Sunil BR, Sampath Kumar TS, Chakkingal U, Nandakumar V, Doble M, Prasad VD, Raghunath M (2016) In vitro and in vivo studies of biodegradable fine grained AZ31 magnesium alloy produced by equal channel angular pressing. Mater Sci Eng C 59:356–367CrossRefGoogle Scholar
  15. 15.
    Huo W, Lin X, Lv L, Cao H, Yu S, Yu Z, Zhang Y (2018) Manipulating the degradation behavior and biocompatibility of Mg alloy through a two-step treatment combining sliding friction treatment and micro-arc oxidation. J Mater Chem B 6:6431–6443CrossRefGoogle Scholar
  16. 16.
    Sunil BR, Kumar AA, Kumar TSS, Chakkingal U (2013) Role of biomineralization on the degradation of fine grained AZ31 magnesium alloy processed by groove pressing. Mater Sci Eng C 33:1607–1615CrossRefGoogle Scholar
  17. 17.
    Kim HS, Kim WJ (2013) Enhanced corrosion resistance of ultrafine-grained AZ61 alloy containing very fine particles of Mg17Al12 phase. Corros Sci 75:228–238CrossRefGoogle Scholar
  18. 18.
    Orlov D, Ralston KD, Birbilis N, Estrin Y (2011) Enhanced corrosion resistance of Mg alloy ZK60 after processing by integrated extrusion and equal channel angular pressing. Acta Mater 59:6176–6186CrossRefGoogle Scholar
  19. 19.
    Valiev RZ, Estrin Y, Horita Z, Langdon TG, Zehetbauer MJ, Zhu Y (2016) Producing bulk ultrafine-grained materials by severe plastic deformation: ten years later. JOM 68:1216–1226CrossRefGoogle Scholar
  20. 20.
    Huo WT, Zhao LZ, Yu S, Yu ZT, Zhang PX, Zhang YS (2017) Significantly enhanced osteoblast response to nano-grained pure tantalum. Sci Rep 7:40868CrossRefGoogle Scholar
  21. 21.
    Zhang YS, Zhang PX, Niu HZ, Chen C, Wang G, Xiao DH, Chen XH, Yu ZT, Yuan SB, Bai XF (2014) Surface nanocrystallization of Cu and Ta by sliding friction. Mater Sci Eng A 607:351–355CrossRefGoogle Scholar
  22. 22.
    Lu J, Zhang Y, Huo W, Zhang W, Zhao Y, Zhang Y (2018) Electrochemical corrosion characteristics and biocompatibility of nanostructured titanium for implants. Appl Surf Sci 434:63–72CrossRefGoogle Scholar
  23. 23.
    Li C, Cui W, Zhang Y (2017) Surface self-nanocrystallization of α + β titanium alloy by surface mechanical grinding treatment. Metals Mater Int 23:512–518CrossRefGoogle Scholar
  24. 24.
    Huo WT, Zhao LZ, Zhang W, Lu JW, Zhao YQ, Zhang YS (2018) In vitro corrosion behavior and biocompatibility of nanostructured Ti6Al4V. Mater Sci Eng C 92:268–279CrossRefGoogle Scholar
  25. 25.
    Zhang W, Lu J, Huo W, Zhang Y, Wei Q (2018) Microstructural evolution of AZ31 magnesium alloy subjected to sliding friction treatment. Philos Mag 98:1576–1593CrossRefGoogle Scholar
  26. 26.
    Huo WT, Zhang W, Lu JW, Zhang YS (2017) Simultaneously enhanced strength and corrosion resistance of Mg–3Al–1Zn alloy sheets with nano-grained surface layer produced by sliding friction treatment. J Alloys Compd 720:324–331CrossRefGoogle Scholar
  27. 27.
    Zhang YS, Wei QM, Niu HZ, Li YS, Chen C, Yu ZT, Bai XF, Zhang PX (2014) Formation of nanocrystalline structure in tantalum by sliding friction treatment. Int J Ref Metals Hard Mater 45:71–75CrossRefGoogle Scholar
  28. 28.
    Kokubo T, Takadama H (2006) How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 27:2907–2915CrossRefGoogle Scholar
  29. 29.
    Xu R, Yang X, Li P, Suen KW, Wu G, Chu PK (2014) Eelectrochemical properties and corrosion resistance of carbon-ion-implanted magnesium. Corros Sci 82:173–179CrossRefGoogle Scholar
  30. 30.
    Kim YK, Jang YS, Lee YH, Yi HK, Bae TS, Lee MH (2017) Effect of Ca–P compound formed by hydrothermal treatment on biodegradation and biocompatibility of Mg–3Al–1Zn–1.5Ca alloy: in vitro and in vivo evaluation. Sci Rep 7:712CrossRefGoogle Scholar
  31. 31.
    Shi YJ, Pei J, Zhang J, Niu JL, Zhang H, Guo SR, Li ZH, Yuan GY (2017) Enhanced corrosion resistance and cytocompatibility of biodegradable Mg alloys by introduction of Mg(OH)2 particles into poly (l-lactic acid) coating. Sci Rep 7:41796CrossRefGoogle Scholar
  32. 32.
    Jin W, Wang G, Lin Z, Feng H, Li W, Peng X, Qasim AM, Chu PK (2017) Corrosion resistance and cytocompatibility of tantalum-surface-functionalized biomedical ZK60 Mg alloy. Corros Sci 114:45–56CrossRefGoogle Scholar
  33. 33.
    Song Y, Shan D, Chen R, Zhang F, Han EH (2009) Biodegradable behaviors of AZ31 magnesium alloy in simulated body fluid. Mater Sci Eng C 29:1039–1045CrossRefGoogle Scholar
  34. 34.
    Pu Z, Song GL, Yang S, Outeiro JC, Dillon OW, Puleo DA, Jawahir IS (2012) Grain refined and basal textured surface produced by burnishing for improved corrosion performance of AZ31B Mg alloy. Corros Sci 57:192–201CrossRefGoogle Scholar
  35. 35.
    Razavi M, Fathi M, Savabi O, Vashaee D, Tayebi L (2014) In vitro study of nanostructured diopside coating on Mg alloy orthopedic implants. Mater Sci Eng C 41:168–177CrossRefGoogle Scholar
  36. 36.
    Razavi M, Fathi M, Savabi O, Hashemi Beni B, Vashaee D, Tayebi L (2014) Surface microstructure and in vitro analysis of nanostructured akermanite (Ca2MgSi2O7) coating on biodegradable magnesium alloy for biomedical applications. Colloids Surf B Biointerfaces 117:432–440CrossRefGoogle Scholar
  37. 37.
    Razavi M, Fathi M, Savabi O, Vashaee D, Tayebi L (2015) In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications. Mater Sci Eng C 48:21–27CrossRefGoogle Scholar
  38. 38.
    Hiromoto S, Inoue M, Taguchi T, Yamane M, Ohtsu N (2015) In vitro and in vivo biocompatibility and corrosion behaviour of a bioabsorbable magnesium alloy coated with octacalcium phosphate and hydroxyapatite. Acta Biomater 11:520–530CrossRefGoogle Scholar
  39. 39.
    Zhao Y, Wu G, Jiang J, Wong HM, Yeung KWK, Chu PK (2012) Improved corrosion resistance and cytocompatibility of magnesium alloy by two-stage cooling in thermal treatment. Corros Sci 59:360–365CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Northwest Institute for Nonferrous Metal ResearchXi’anChina
  2. 2.Orthopaedic Institute, Medical CollegeSoochow UniversitySuzhouChina
  3. 3.Xi’an Rare Metal Materials Institute Co., LtdXi’anChina

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