Journal of Materials Science

, Volume 53, Issue 1, pp 447–455 | Cite as

Dopamine modified polyaniline with improved adhesion, dispersibility, and biocompatibility

Chemical routes to materials
First Online:
Received:
Accepted:

Abstract

Dopamine (DA), a biological neurotransmitter which has a similar structure to the essential adhesive component of mussel protein, was here used to modify polyaniline (PANI) via a one-step chemical oxidization method. The as-fabricated DA-PANI resulted from different DA to aniline (An) mole ratio showed different morphology. Compared to pure PANI, the modified PANI exhibited greatly enhanced adhesion force to the substrate. In addition, the biocompatibility and dispersibility of DA-modified PANI were also significantly improved compared with pure PANI. More importantly, the incorporation of poor conductive PDA did not enormously weaken the electrical conductivity of PANI, and it still showed good electrical conductivity as the DA/An mole ratio was not higher than 0.48.

This is a preview of subscription content, log in to check access.

Notes

Acknowledgements

This work was supported by the National Nature Science Foundation of China (31271009, 81271689), the Fundamental Research Funds for the Central Universities (No. 2011121001), the Program for New Century Excellent Talents in University, and the Program for New Century Excellent Talents in Fujian Province University and the Xiamen Municipal Science and Technology project (3502Z20144026).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

References

  1. 1.
    Huang S, Liang N, Hu Y, Zhou X, Abidi N (2016) Polydopamine-assisted surface modification for bone biosubstitutes. Biomed Res Int 2016:2389895Google Scholar
  2. 2.
    Ye Q, Zhou F, Liu W (2011) Bioinspired catecholic chemistry for surface modification. Chem Soc Rev 40:4244–4258CrossRefGoogle Scholar
  3. 3.
    Fan X, Lin L, Dalsin JL, Messersmith PB (2005) Biomimetic anchor for surface-initiated polymerization from metal substrates. J Am Chem Soc 127:15843–15847CrossRefGoogle Scholar
  4. 4.
    Lee H, Dellatore SM, Miller WM, Messersmith PB (2007) Mussel-inspired surface chemistry for multifunctional coatings. Science 318:426–430CrossRefGoogle Scholar
  5. 5.
    Liu Y, Ai K, Lu L (2014) Polydopamine and its derivative materials: synthesis and promising applications in energy, environmental, and biomedical fields. Chem Rev 114:5057–5115CrossRefGoogle Scholar
  6. 6.
    Son EJ, Kim JH, Kim K, Park CB (2016) Quinone and its derivatives for energy harvesting and storage materials. J Mater Chem A 4:11179–11202CrossRefGoogle Scholar
  7. 7.
    Liu Y, Ai K, Liu J, Deng M, He Y, Lu L (2013) Dopamine-melanin colloidal nanospheres: an efficient near-infrared photothermal therapeutic agent for in vivo cancer therapy. Adv Mater 25:1353–1359CrossRefGoogle Scholar
  8. 8.
    Tian J, Deng SY, Li DL, Shan D, He W, Zhang XJ, Shi Y (2013) Bioinspired polydopamine as the scaffold for the active AuNPs anchoring and the chemical simultaneously reduced graphene oxide: characterization and the enhanced biosensing application. Biosens Bioelectron 49:466–471CrossRefGoogle Scholar
  9. 9.
    Kim JH, Lee M, Park CB (2014) Inside cover: polydopamine as a biomimetic electron gate for artificial photosynthesis (Angew. Chem. Int. Ed. 25/2014). Angewandte Chemie 53:6364–6368CrossRefGoogle Scholar
  10. 10.
    Gao H, Sun Y, Zhou J, Xu R, Duan H (2013) Mussel-inspired synthesis of polydopamine-functionalized graphene hydrogel as reusable adsorbents for water purification. ACS Appl Mater Interf 5:425–433CrossRefGoogle Scholar
  11. 11.
    Zhang W, Yang FK, Pan ZH, Zhang J, Zhao BX (2014) Bio-inspired dopamine functionalization of polypyrrole for improved adhesion and conductivity. Macromol Rapid Commun 35:350–354CrossRefGoogle Scholar
  12. 12.
    Zhang W, Pan Z, Yang FK, Zhao B (2015) A facile in situ approach to polypyrrole functionalization through bioinspired catechols. Adv Func Mater 25:1588–1597CrossRefGoogle Scholar
  13. 13.
    Kim S, Jang LK, Park HS, Lee JY (2016) Electrochemical deposition of conductive and adhesive polypyrrole-dopamine films. Scientific Rep 6:30475CrossRefGoogle Scholar
  14. 14.
    Wang Z, Zhou L, Yu P, Liu Y, Chen J, Liao J, Li W, Chen W, Zhou W, Yi X, Ouyang K, Zhou Z, Tan G, Ning C (2016) Polydopamine-assisted electrochemical fabrication of polypyrrole nanofibers on bone implants to improve bioactivity. Macromol Mater Eng 301:1288–1294CrossRefGoogle Scholar
  15. 15.
    Li C, Bai H, Shi G (2009) Conducting polymer nanomaterials: electrosynthesis and applications. Chem Soc Rev 38:2397–2409CrossRefGoogle Scholar
  16. 16.
    Oh W-K, Kwon OS, Jang J (2013) Conducting polymer nanomaterials for biomedical applications: cellular interfacing and biosensing. Polym Rev 53:407–442CrossRefGoogle Scholar
  17. 17.
    Tran HD, Li D, Kaner RB (2009) One-dimensional conducting polymer nanostructures: bulk synthesis and applications. Adv Mater 21:1487–1499CrossRefGoogle Scholar
  18. 18.
    Llorens E, Armelin E, del Mar Pérez-Madrigal M, del Valle L, Alemán C, Puiggalí J (2013) Nanomembranes and nanofibers from biodegradable conducting polymers. Polymers 5:1115–1157CrossRefGoogle Scholar
  19. 19.
    Borriello A, Guarino V, Schiavo L, Alvarezperez MA, Ambrosio L (2011) Optimizing PANi doped electroactive substrates as patches for the regeneration of cardiac muscle. J Mater Sci Mater Med 22:1053–1062CrossRefGoogle Scholar
  20. 20.
    Zhang QS, Yan YH, Li SP, Feng T (2009) Synthesis of a novel biodegradable and electroactive polyphosphazene for biomedical application. Biomed Mater 4:035008CrossRefGoogle Scholar
  21. 21.
    Huang L, Zhuang X, Hu J (2008) Synthesis of biodegradable and electroactive multiblock polylactide and aniline pentamer copolymer for tissue engineering applications. Biomacromolecules 9:850–858CrossRefGoogle Scholar
  22. 22.
    Qazi TH, Rai R, Boccaccini AR (2014) Tissue engineering of electrically responsive tissues using polyaniline based polymers: a review. Biomaterials 35:9068–9086CrossRefGoogle Scholar
  23. 23.
    Yu QZ, Shi MM, Deng M, Wang M, Chen HZ (2008) Morphology and conductivity of polyaniline sub-micron fibers prepared by electrospinning. Mater Sci Eng, B 150:70–76CrossRefGoogle Scholar
  24. 24.
    Li F, Yang L, Zhao C, Du Z (2011) Electroactive gold nanoparticles/polyaniline/polydopamine hybrid composite in neutral solution as high-performance sensing platform. Anal Methods 3:1601–1607CrossRefGoogle Scholar
  25. 25.
    Mihai I, Addiégo F, Del Frari D, Bour J, Ball V (2013) Associating oriented polyaniline and eumelanin in a reactive layer-by-layer manner: composites with high electrical conductivity. Colloids Surf, A 434:118–125CrossRefGoogle Scholar
  26. 26.
    Moon IJ, Kim MW, Choi HJ, Kim N, You C-Y (2016) Fabrication of dopamine grafted polyaniline/carbonyl iron core-shell typed microspheres and their magnetorheology. Colloids Surf, A 500:137–145CrossRefGoogle Scholar
  27. 27.
    Wang H-B, Zhang H-D, Jiang Y-L, Li X-L, Liu Y-M (2015) Determination of adenine and guanine by a dopamine-melanin nanosphere-polyaniline nanocomposite modified glassy carbon electrode. Anal Lett 49:226–235CrossRefGoogle Scholar
  28. 28.
    Wang X, Lee PS (2015) A polydopamine coated polyaniline single wall carbon nanotube composite material as a stable supercapacitor cathode in an organic electrolyte. J Mater Res 30:3575–3583CrossRefGoogle Scholar
  29. 29.
    Xie C, Li P, Han L, Wang Z, Zhou T, Deng W, Wang K, Lu X (2017) Electroresponsive and cell-affinitive polydopamine/polypyrrole composite microcapsules with a dual-function of on-demand drug delivery and cell stimulation for electrical therapy. NPG Asia Mater 9:e358CrossRefGoogle Scholar
  30. 30.
    Boomi P, Prabu HG, Mathiyarasu J (2013) Synthesis and characterization of polyaniline/Ag-Pt nanocomposite for improved antibacterial activity. Colloids Surf B Biointerfaces 103:9–14CrossRefGoogle Scholar
  31. 31.
    Boomi P, Prabu HG, Mathiyarasu J (2014) Synthesis, characterization and antibacterial activity of polyaniline/Pt-Pd nanocomposite. Eur J Med Chem 72:18–25CrossRefGoogle Scholar
  32. 32.
    Eisa WH, Zayed MF, Abdel-Moneam YK, Zeid AMA (2014) Water-soluble gold/polyaniline core/shell nanocomposite: synthesis and characterization. Synth Met 195:23–28CrossRefGoogle Scholar
  33. 33.
    Shabana S, Sonawane SH, Ranganathan V, Pujjalwar PH, Pinjari DV, Bhanvase BA, Gogate PR, Ashokkumar M (2017) Improved synthesis of aluminium nanoparticles using ultrasound assisted approach and subsequent dispersion studies in di-octyl adipate. Ultrason Sonochem 36:59–69CrossRefGoogle Scholar
  34. 34.
    Wang J, Zhang K, Zhao L (2014) Sono-assisted synthesis of nanostructured polyaniline for adsorption of aqueous Cr(VI): effect of protonic acids. Chem Eng J 239:123–131CrossRefGoogle Scholar
  35. 35.
    DE Medeiros DSDSDWO, Dantas TNC, Perira MR, Giacometi JA, Fonseca JLC (2003) Zeta potential and doping in polyaniline dispersions. Mater Sci 21:251–258Google Scholar
  36. 36.
    Jastrzebska MM, Isotalo H, Paloheimo J, Stubb H (1996) Electrical conductivity of synthetic DOPA-melanin polymer for different hydration states and temperatures. J Biomater Sci Polym Ed 7:577–586CrossRefGoogle Scholar
  37. 37.
    Balint R, Cassidy NJ, Cartmell SH (2014) Conductive polymers: towards a smart biomaterial for tissue engineering. Acta Biomater 10:2341–2353CrossRefGoogle Scholar
  38. 38.
    Bidez PR, Li S, MacDiarmid AG, Venancio EC, Wei Y, Lelkes PI (2006) Polyaniline, an electroactive polymer, supports adhesion and proliferation of cardiac myoblasts. J Biomater Sci Polym Ed 17:199–212CrossRefGoogle Scholar
  39. 39.
    Gilmore KJ, Kita M, Han Y, Gelmi A, Higgins MJ, Moulton SE, Clark GM, Kapsa R, Wallace GG (2009) Skeletal muscle cell proliferation and differentiation on polypyrrole substrates doped with extracellular matrix components. Biomaterials 30:5292–5304CrossRefGoogle Scholar
  40. 40.
    Guo Y, Li M, Mylonakis A, Han J, Macdiarmid AG, Chen X, Lelkes PI, Wei Y (2007) Electroactive oligoaniline-containing self-assembled monolayers for tissue engineering applications. Biomacromolecules 8:3025–3034CrossRefGoogle Scholar
  41. 41.
    Humpolicek P, Kasparkova V, Saha P, Stejskal J (2012) Biocompatibility of polyaniline. Synth Met 162:722–727CrossRefGoogle Scholar
  42. 42.
    Zhang W, Zhou YK, Feng K, Trinidad J, Yu AP, Zhao BX (2015) Morphologically controlled bioinspired dopamine-polypyrrole nanostructures with tunable electrical properties. Adv Electron Mater 1:205–214Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  1. 1.Department of Biomaterials, College of MaterialsXiamen UniversityXiamenChina
  2. 2.Department of StomatologyThe Affiliated Zhongshan Hospital of Xiamen UniversityXiamenChina

Personalised recommendations