Journal of Materials Science

, Volume 51, Issue 15, pp 7156–7169 | Cite as

Hollow MnS nanospheres as electron transfer promoters of hemoglobin and their electrochemical sensing applications

  • Suyu He
  • Weiwei Qiu
  • Liheng Wang
  • Feng Gao
  • Wei Wang
  • Zhengshui Hu
  • Qingxiang WangEmail author
Original Paper


Monodispersed hollow MnS nanospheres have been prepared through a solvothermal method using an imidazoline derivative as the morphology-directing reagent. The composition and morphology of synthesized MnS were characterized by powder XRD, SEM, and TEM. The MnS nanospheres were then mixed with chitosan and used as an immobilization matrix for redox protein of hemoglobin. UV–vis and FT-IR spectra showed that the configuration of hemoglobin in the composite film was well maintained. Electrochemical experiments demonstrated that the charge transfer process of Hb was greatly promoted by the MnS. The modified electrode also showed good electrocatalysis toward hydrogen peroxide with the linear range from 0.8 to 15.2 µM. The detection limit and Michaelis–Menten constant were determined to be 0.092 and 4.33 µM, respectively. When the biosensor was utilized for the detection of hydrogen peroxide in contact lens care solution, satisfactory results were obtained.


Chitosan Composite Film Cathodic Peak Redox Peak Bi2S3 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The work is supported by the National Natural Science Foundation of China (No. 21275127), Education-Science Research Project for Young and Middle-aged Teachers of Fujian (No. JA15305), and Education Department of Fujian Province (No. JA14195).


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Suyu He
    • 1
  • Weiwei Qiu
    • 1
  • Liheng Wang
    • 1
  • Feng Gao
    • 1
    • 2
  • Wei Wang
    • 2
  • Zhengshui Hu
    • 2
  • Qingxiang Wang
    • 1
    Email author
  1. 1.College of Chemistry and Environment, Fujian Province Key Laboratory of Morden Analytical Science and Separation TechnologyMinnan Normal UniversityZhangzhouPeople’s Republic of China
  2. 2.College of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdaoPeople’s Republic of China

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